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IL-13 Protein & Antibody (ALRH)

Interleukin 13

IL-13 Alternative Names

IL-13, ALRH, BHR1, MGC116786, MGC116788, MGC116789, P600

IL-13 Protein & Antibody

Sino Biological offers a comprehensive set of research tools (proteins, antibodies) for interleukin related research. We offer more than 50 high-quality, human cell-expressed interleukin & receptor recombinant proteins from human, mouse or rhesus. Our antibody products include mouse monoclonal and rabbit polyclonal antibodies for application such as ELISA, Western Blotting, IHC, etc. All of our antibodies were generated with recombinant full length protein as immunogen, which ensures better binding affinity and specificity to the native protein.

IL-13 Protein, Recombinant

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
IL-13/ALRH Human IL-13 / ALRH / IL13 / Fc Protein, Recombinant 10369-H01H
IL-13/ALRH Human IL-13 / ALRH / IL13 Protein, Recombinant 10369-HNAC
IL-13/ALRH Mouse IL-13 / Interleukin-13 / ALRH / IL13 Protein, Recombinant, with Native 50225-MNAH
IL-13/ALRH Cynomolgus IL-13 / ALRH / IL13 Protein, Recombinant 11057-CNAH
IL-13/ALRH Cynomolgus IL-13 / ALRH / IL13 Protein, Recombinant 11057-C07H

  10369-HNAC:  The ED50 for this effect is typically 1.5 ng/mL.Measured in a cell proliferation assay using TF1 human erythroleukemic cells. (Kitamura, T. et al. 1989, J. Cell Physiol. 140:323.).

  11057-CNAH:  The ED50 for this effect is typically 2-8 ng/mL..Measured in a cell proliferation assay using TF-1 human erythroleukemic cells.

  11057-C07H:

1. Immobilized cynomolgus IL-13 at 4 μg/ml (100 μl/well) can bind human IL13RA1 with a linear ranger of  0.156-2.5 μg/ml. Measured by its binding ability in a functional ELISA.

2. The specific activity is 5-20 ng/ml. Measured in a cell proliferation assay using TF-1 human erythroleukemic cells.

IL-13 Antibody

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human IL-13/ALRH ELISA IL-13 / ALRH / IL13 Mouse MAb 10369-MM01
Human IL-13/ALRH WB IL-13 / ALRH / IL13 Mouse MAb 10369-MM02
Human IL-13/ALRH WB, ELISA IL13 / ALRH / IL13 Antibody (Antigen Affinity Purified) 10369-RP02
Human IL-13/ALRH WB, ELISA IL13 / ALRH / IL13 Antibody 10369-R062

IL-13 Cell Lysates

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
IL-13/ALRH Mouse Mouse IL-13 / Interleukin-13 Human Cells Transfected Lysate (positive control) (denatured) 50225-MNAHL
IL-13/ALRH Cynomolgus Cynomolgus IL-13 / Interleukin-13 Human Cells Transfected Lysate (positive control) (denatured) 11057-CNAHL

IL-13 cDNA Clone

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
IL-13/ALRH Human Human IL-13/ALRH Gene cDNA Clone / ORF Clone HG10369-M
IL-13/ALRH Mouse Mouse IL13/ALRH Gene cDNA Clone / ORF Clone MG50225-M

IL-13 Related Areas

Cancer>>Angiogenesis>>Cytokines/Chemokines in Angiogenesis>>IL-13

Immunology>>Adaptive Immunity>>B Cell>>IL-13

Immunology>>Adaptive Immunity>>T Cell>>Helper T Cell>>IL-13

Immunology>>Cytokine & Receptor>>Interleukin & Receptor>>Other>>IL-13

IL-13 Related Products

Protein Products
Molecule Species Description //For Detailed Info. and Price------CLICK!
IL-13RA1 Human IL-13RA1 Protein, Recombinant
IL-13RA1 Human IL-13RA1 / Fc Protein, Recombinant
IL-13RA1 Mouse IL-13RA1 / Fc Protein, Recombinant
IL-13RA1 Mouse IL-13RA1 Protein, Recombinant
IL-13RA2 Human IL-13RA2 / Fc Protein, Recombinant
IL-13RA2 Mouse IL-13RA2 Protein, Recombinant
IL-13RA2 Mouse IL-13RA2 / Fc Protein, Recombinant
Antibody Products
Molecule Species Description //For Detailed Info. and Price------CLICK!
Human
IL-13RA1
WB, ELISA IL13RA1 Antibody, Mouse MAb
Human
IL-13RA1
ELISA IL13RA1 Antibody, Rabbit MAb
Human
IL-13RA1
WB IL13RA1 Antibody, Rabbit MAb
Human
IL-13RA1
WB, ELISA IL13RA1 Rabbit PAb
Human
IL-13RA1
WB, ELISA IL13RA1 Rabbit PAb (Antigen Affinity Purified)
Mouse
IL-13RA1
WB, ELISA IL13RA1 Antibody, Rabbit MAb
Mouse
IL-13RA1
WB, ELISA IL-13RA1 Rabbit PAb
Mouse
IL-13RA1
WB, ELISA IL-13RA1 Rabbit PAb (Antigen Affinity Purified)
Mouse
IL-13RA2
WB, ELISA IL13RA2 / CD213a2 Antibody, Rabbit MAb
Mouse
IL-13RA2
WB, ELISA IL-13RA2 Rabbit PAb
Mouse
IL-13RA2
WB, ELISA IL-13RA2 Rabbit PAb (Antigen Affinity Purified)
cDNA Clone Products
Molecule Species Description //For Detailed Info. and Price------CLICK!
IL-13/ALRH Human Homo sapiens IL-13 / ALRH cDNA Clone(NM_002188.2)
IL-13Ra1 Human Homo sapiens IL-13Ra1 cDNA Clone(NM_001560.2)
IL-13RA1 Mouse Mus musculus IL-13RA1 cDNA Clone
IL-13Ra2 Human Homo sapiens IL-13Ra2 cDNA Clone(NM_000640.2)
IL-13Ra2 Mouse Mus musculus IL-13Ra2 cDNA Clone

IL-13 Background

Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses and diseases. In addition, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody is more importantly implicated as a central mediator of immunoregulatory processes in various cell types.

IL-13 Related Studies

  1. Junttila IS, et al. (2008) Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. J Exp Med. 205(11): 2595-608.
  2. Shimamura T,et al. (2008) Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat model. J Immunol. 181(7): 4656-65.

 

 

IL13 related areas, pathways, and other information

 

 

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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