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IL13 / ALRH Antibody, Rabbit PAb, Antigen Affinity Purified

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Cynomolgus IL13/ALRH Antibody Product Information
Immunogen:Recombinant Cynomolgus IL-13 protein (Catalog#11057-C07H)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:Produced in rabbits immunized with purified, recombinant Cynomolgus IL-13 (rC IL-13; Catalog#11057-C07H; ABG75889.1; Ser 21-Asn 132). IL-13 specific IgG was purified by Cynomolgus IL-13 affinity chromatography.
Cynomolgus IL13/ALRH Antibody Usage Guide
Specificity:Cynomolgus IL-13
Application:ELISA

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Cynomolgus IL13. The detection limit for Cynomolgus IL13 is approximately 0.039 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other IL13/ALRH Antibody Products
Reactivity: Human  
Application: ELISA  
    10369-MM01-200
    10369-MM01-50
    10369-MM01-100
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    Reactivity: Human  
    Application: ELISA  
      10369-RP02-200
      10369-RP02-50
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      Reactivity: Human  
      Application: ELISA  
        10369-R062-50
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        Reactivity: Human  
        Application: ELISA  
          10369-RP01-200
          10369-RP01-100
          10369-RP01-400
          200 µg 
          100 µg 
           
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          Reactivity: Cynomolgus  
          Application: ELISA  
            11057-RP01-200
            11057-RP01-100
            11057-RP01-400
            200 µg 
            100 µg 
             
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            IL13/IL-13/ALRH Background

            Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses and diseases. In addition, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody is more importantly implicated as a central mediator of immunoregulatory processes in various cell types.

            Cynomolgus IL13/IL-13/ALRH References
          • Junttila IS, et al. (2008) Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. J Exp Med. 205(11): 2595-608.
          • Shimamura T,et al. (2008) Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat model. J Immunol. 181(7): 4656-65.
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            Catalog: 11057-RP02-50
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            All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
            Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"