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IL13/IL-13 Mouse MAb

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    Human IL13/ALRH Antibody Product Information
    Immunogen:Recombinant Human IL13 protein (Catalog#10369-H01H)
    Clone ID:4C10A7B3
    Ig Type:Mouse IgG1
    Concentration:
    Endotoxin:
    Formulation:0.2 μm filtered solution in PBS with 5% trehalose
    Preparation:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human interleukin-13 (rh IL-13; Catalog#10369-H01H; Gly 35-Asn 146; NP_002179.2). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
    Other IL13/ALRH Antibody Products
    Reactivity: Human  
    Application: ELISA  
      10369-RP02-200
      10369-RP02-50
      10369-RP02-100
      200 µg 
      50 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  
        10369-R062-50
        10369-R062-100
        50 µg 
        100 µg 
        Add to Cart
        Reactivity: Human  
        Application: ELISA  
          10369-RP01-200
          10369-RP01-100
          10369-RP01-400
          200 µg 
          100 µg 
           
          Add to Cart
          Reactivity: Cynomolgus  
          Application: ELISA  
            11057-RP01-200
            11057-RP01-100
            11057-RP01-400
            200 µg 
            100 µg 
             
            Add to Cart
            Reactivity: Cynomolgus  
            Application: ELISA  
              11057-RP02-50
              11057-RP02-100
              11057-RP02-200
              50 µg 
              100 µg 
              200 µg 
              Add to Cart
              IL13/IL-13 Background

              Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses and diseases. In addition, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody is more importantly implicated as a central mediator of immunoregulatory processes in various cell types.

              Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

              Human IL13/IL-13 References
            • Junttila IS, et al. (2008) Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. J Exp Med. 205(11): 2595-608.
            • Shimamura T,et al. (2008) Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat model. J Immunol. 181(7): 4656-65.
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              Catalog: 10369-MM01-200
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              Datasheet & Documentation

              All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
              Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"