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IL13 / ALRH Antibody, Mouse MAb

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Human IL13/ALRH Antibody Product Information
Immunogen:Recombinant Human IL13 protein (Catalog#10369-H01H)
Clone ID:4C10A7B3
Ig Type:Mouse IgG1
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human interleukin-13 (rh IL-13; Catalog#10369-H01H; Gly 35-Asn 146; NP_002179.2). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Human IL13/ALRH Antibody Usage Guide
Specificity:Human IL13 / ALRH
Has cross-reactivity in ELISA with
Mouse IL13 / ALRH
Application:ELISA

ELISA: 0.5-1 μg/mL

This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human IL13. The detection limit for Human IL13 is approximately 1.25 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other IL13/ALRH Antibody Products
Reactivity: Human  
Application: ELISA  
    10369-RP02-200
    10369-RP02-50
    10369-RP02-100
    200 µg 
    50 µg 
    100 µg 
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    Reactivity: Human  
    Application: ELISA  
      10369-R062-50
      10369-R062-100
      50 µg 
      100 µg 
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      Reactivity: Human  
      Application: ELISA  
        10369-RP01-200
        10369-RP01-100
        10369-RP01-400
        200 µg 
        100 µg 
         
        Add to Cart
        Reactivity: Cynomolgus  
        Application: ELISA  
          11057-RP01-200
          11057-RP01-100
          11057-RP01-400
          200 µg 
          100 µg 
           
          Add to Cart
          Reactivity: Cynomolgus  
          Application: ELISA  
            11057-RP02-50
            11057-RP02-100
            11057-RP02-200
            50 µg 
            100 µg 
            200 µg 
            Add to Cart
            IL13/IL-13/ALRH Background

            Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses and diseases. In addition, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody is more importantly implicated as a central mediator of immunoregulatory processes in various cell types.

            Human IL13/IL-13/ALRH References
          • Junttila IS, et al. (2008) Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. J Exp Med. 205(11): 2595-608.
          • Shimamura T,et al. (2008) Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat model. J Immunol. 181(7): 4656-65.
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            Catalog: 10369-MM01-200
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            All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
            Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"