Anti-IL-13 Antibody

Cat: 10369-MM01
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All IL-13 Reagents
Anti-IL-13 Antibody (Mouse Monoclonal antibody) General Information
Product name
Anti-IL-13 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human IL-13
Has cross-reactivity in ELISA with Mouse IL13 / ALRH
Immunogen
Recombinant Human IL13 protein (Catalog#10369-H01H)
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human interleukin-13 (rh IL-13; Catalog#10369-H01H; Gly 35-Asn 146; NP_002179.2). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Source
Monoclonal Mouse IgG1 Clone #4C10A7B3
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-IL-13 Antibody (Mouse Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-IL-13 Antibody Alternative Names
Anti-ALRH Antibody;Anti-IL-13 Antibody;Anti-P600 Antibody
IL-13 Background Information

Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses and diseases. In addition, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody is more importantly implicated as a central mediator of immunoregulatory processes in various cell types.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
interleukin 13
References
  • Junttila IS, et al. (2008) Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. J Exp Med. 205(11): 2595-608.
  • Shimamura T,et al. (2008) Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat model. J Immunol. 181(7): 4656-65.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-IL-13 Antibody Rabbit Polyclonal ELISA 11057-RP01
    Anti-IL-13 Antibody Rabbit Polyclonal ELISA 11057-RP02
    Anti-IL-13 Antibody Mouse Monoclonal ELISA(Det) 10369-MM02T
    Anti-IL-13 Antibody Mouse Monoclonal ELISA(Cap) 10369-MM15
    Anti-IL-13 Antibody Rabbit Polyclonal ELISA 10369-RP02
    Anti-IL-13 Antibody Rabbit Monoclonal ELISA 10369-R062
    Anti-IL-13 Antibody Rabbit Polyclonal ELISA 10369-RP01
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