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IL-11 / interleukin 11  Protein, Antibody, ELISA Kit, cDNA Clone

Expression host: E. coli  
  • Slide 1
  • Slide 1
12225-HNCE-50
12225-HNCE-5
12225-HNCE-20
12225-HNCE-10
50 µg 
5 µg 
20 µg 
10 µg 
Add to Cart
Expression host: E. coli  
  • Slide 1
50117-MNCE-50
50117-MNCE-5
50117-MNCE-100
50117-MNCE-10
50 µg 
5 µg 
100 µg 
10 µg 
Add to Cart

IL-11 / interleukin 11 Related Area

IL-11 / interleukin 11 Related Pathways

    IL-11 / interleukin 11 Related Protein, Antibody, cDNA Gene, and ELISA Kits

    IL-11 / interleukin 11 Related Protein, Antibody, cDNA Gene, and ELISA Kits

    IL-11 / interleukin 11 Summary & Protein Information

    IL-11 / interleukin 11 Background

    Subcellular location: Secreted.
    Sequence similarity: Belongs to the IL-6 superfamily.
    General information above from UniProt

    IL11 is a multifunctional cytokine first isolated in 1990 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 is also known under the names adipogenesis inhibitory factor (AGIF) and oprelvekin. IL11 can improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation and could be use as a therapeutic for osteoporosis. IL11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. As a signaling molecule, IL11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; such functions include placentation and to some extent of decidualization.

    IL-11 / interleukin 11 Alternative Name

    AGIF,IL-11, [homo-sapiens]
    interleukin 11,IL11,AGIF,IL-11,adipogenesis inhibitory factor,oprelvekin, [human]
    interleukin 11,Il11,IL-11, [mouse]
    IL-11, [mus-musculus]

    IL-11 / interleukin 11 Related Studies

  • McKinley D. et al., 1992, Genomics. 13 (3): 814-9.
  • Paul SR. et al., 1990, Proc Natl Acad Sci. 87 (19): 7512-6.
  • Kawashima I. et al., 1991, FEBS Lett. 283 (2): 199-202.
  • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"