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IL1B / IL-1 beta Protein & Antibody (IL1F2)

Interleukin-1 beta (IL-1 family member 2)

IL-1 beta Products

IL-1 beta Protein, Recombinant

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
IL-1 beta/IL-1F2 Human IL-1 beta / IL-1F2 / IL1B Protein, Recombinant 10139-HNAE
IL-1 beta/IL-1F2 Human IL-1 beta / IL-1F2 / IL1B (pro form) Protein, Recombinant 10139-H07E
IL-1 beta/IL-1F2 Mouse IL-1 beta / IL-1F2 / IL1B Protein, Recombinant 50101-MNAE
IL-1 beta/IL-1F2 Rat IL-1 beta / IL-1F2 / IL1B (mature form) Protein, Recombinant, Native 80023-RNAE
IL-1 beta/IL-1F2 Rat IL-1 beta / IL-1F2 / IL1B (pro form) Protein, Recombinant 80023-R07E
IL-1 beta/IL-1F2 Rabbit Rabbit IL-1 beta / IL1B Protein 65004-TNAE
IL-1 beta/IL-1F2 Canine IL-1F2 / IL1B / IL-1beta Protein, Recombinant, untagged 70018-DNAE
IL-1 beta/IL-1F2 Cynomolgus  IL1B / IL-1beta / IL-1F2 Protein, Recombinant, untagged 90010-CNAE

  10139-HNAE:

1. Immobilized recombinant human IL1B at 2 µg/mL (100µl/well) can bind recombinant human  IL1R2 with a linear  range of  6.25-400 ng/ml. Measured by its binding ability in a functional ELISA.

2. The ED50 for this effect is typically 0.5-5 pg/mL. Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells.

  50101-MNAE: The ED50 for this effect is typically 2-10 pg/mL. Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells.

IL-1 beta Antibody

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
IL-1 beta/IL-1F2
WB, ELISA IL-1 beta / IL-1F2 / IL1B Antibody, Rabbit MAb 10139-R012
Human
IL-1 beta/IL-1F2
WB, ELISA IL-1 beta / IL-1F2 / IL1B Antibody, Rabbit PAb 10139-RP01
Human
IL-1 beta/IL-1F2
WB, ELISA IL-1 beta / IL-1F2 / IL1B Antibody, Rabbit PAb (Antigen Affinity Purified) 10139-RP02
Mouse
IL-1 beta/IL-1F2
WB, ELISA IL-1 beta / IL-1F2 / IL1B Antibody (Antigen Affinity Purified) 50101-RP02
Rat
IL-1 beta/IL-1F2
WB, ELISA IL-1 beta / IL-1F2 / IL1B Antibody, Rabbit PAb (Antigen Affinity Purified) 80023-RP02

IL-1 beta ELISA Kits

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
IL-1 beta/IL-1F2
ELISA IL-1 beta / IL1B / IL-1F2 ELISA Pair Set, Human ELISA Pair Set SEK10139

IL-1 beta cDNA Clone

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
IL-1 beta/IL-1F2 Human Homo sapiens IL-1 beta / IL-1F2 / IL1B cDNA Clone(NM_000576.2) HG10139-M
IL-1 beta/IL-1F2 Human Human IL1F2 / IL1B ORF Expression Clone, untagged HG10139-M-N
IL-1 beta/IL-1F2 Mouse Mus IL-1 beta / IL-1F2 / IL1B cDNA Clone MG50101-M
IL-1 beta/IL-1F2 Canine IL-1 beta / IL-1F2 / IL1B cDNA Clone / ORF Clone DG70018-G
IL-1 beta/IL-1F2 Rat Rattus norvegicus IL-1 beta / IL-1F2 / IL1B cDNA Clone RG80023-M
IL-1 beta/IL-1F2 Cynomolgus Cynomolgus IL-1 beta / IL-1F2 / IL1B cDNA Clone / ORF Clone CG90010-M

IL-1 beta Related Areas

Cancer>>Angiogenesis>>Cytokines/Chemokines in Angiogenesis>>IL-1 beta/IL-1F2

Immunology>>Adaptive Immunity>>T Cell>>Helper T Cell>>IL-1 beta/IL-1F2

Immunology>>Cytokine & Receptor>>Interleukin & Receptor>>IL-1 superfamily and IL-1R/TLR family >>IL-1 beta/IL-1F2

IL-1 beta Alternative Names

IL-1 beta, IL1F2, IL1B, IL-1, IL1-BETA

IL1B / IL1beta Background

Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).

IL1B / IL1beta Related Studies

  1. Kim SH, et al. (2008) Association of -31T>C and -511 C>T polymorphisms in the interleukin 1 beta (IL1B) promoter in Korean keratoconus patients. Mol Vis. 14:2109-16.
  2. Wang ZC, et al. (2002) T helper 1-type immunity to trophoblast antigens in women with a history of recurrent pregnancy loss is associated with polymorphism of the IL1B promoter region. Genes Immun. 3(1): 38-42.
  3. Mattuzzi S, et al. (2007) Association of polymorphisms in the IL1B and IL2 genes with susceptibility and severity of systemic sclerosis. J Rheumatol. 34(5): 997-1004.

 

IL-1 beta related areas, pathways, and other information

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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