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IL1B/IL-1B/IL-1 beta Rabbit MAb

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    Human IL1B Antibody Product Information
    Immunogen:Recombinant Human ILb protein (Catalog#10139-HNAE)
    Clone ID:012
    Ig Type:Rabbit IgG
    Concentration:
    Formulation:0.2 μm filtered solution in PBS with 5% trehalose
    Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Human IL1B (rh IL1B; Catalog#10139-HNAE; NP_000567.1; Ala 117-Ser 269).
    Other IL1B Antibody Products
    Reactivity: Human  
    Application: ELISA  
      10139-RP01-400
      10139-RP01-100
      10139-RP01-200
       
      100 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  
        10139-RP02-200
        10139-RP02-50
        10139-RP02-100
        200 µg 
        50 µg 
        100 µg 
        Add to Cart
        Reactivity: Human  
        Application: ELISA  IHC-P  
        • Slide 1
        • Slide 1
        10139-M201-100
        10139-M201-50
        10139-M201-200
        100 µg 
        50 µg 
        200 µg 
        Add to Cart
        Reactivity: Mouse  
        Application: ELISA  
          50101-R020-50
          50101-R020-100
          50 µg 
          100 µg 
          Add to Cart
          Reactivity: Mouse  
          Application: ELISA  
            50101-R001-50
            50101-R001-100
            50 µg 
            100 µg 
            Add to Cart
            Reactivity: Mouse  
            Application: ELISA  
              50101-RP01-400
              50101-RP01-200
              50101-RP01-100
               
              200 µg 
              100 µg 
              Add to Cart
              Reactivity: Mouse  
              Application: ELISA  WB  
              • Slide 1
              50101-RP02-50
              50101-RP02-100
              50101-RP02-200
              50 µg 
              100 µg 
              200 µg 
              Add to Cart
              Reactivity: Mouse  
              Application: ELISA  WB  
              • Slide 1
              50101-T48-200
              50101-T48-100
              50101-T48-50
              200 µg 
              100 µg 
              50 µg 
              Add to Cart
              Reactivity: Rat  
              Application: ELISA  
                80023-T16-50
                80023-T16-100
                80023-T16-200
                50 µg 
                100 µg 
                200 µg 
                Add to Cart
                Reactivity: Rat  
                Application: ELISA  WB  
                • Slide 1
                80023-RP02-50
                80023-RP02-100
                80023-RP02-200
                50 µg 
                100 µg 
                200 µg 
                Add to Cart
                Reactivity: Rat  
                Application: ELISA  
                  80023-RP01-100
                  80023-RP01-200
                  80023-RP01-400
                  100 µg 
                  200 µg 
                   
                  Add to Cart
                  Reactivity: Rat  
                  Application: ELISA  
                    80023-R017-50
                    80023-R017-100
                    50 µg 
                    100 µg 
                    Add to Cart
                    Reactivity: Cynomolgus  
                    Application: ELISA  
                      90010-RP01-100
                      90010-RP01-400
                      90010-RP01-200
                      100 µg 
                       
                      200 µg 
                      Add to Cart
                      Reactivity: Cynomolgus  
                      Application: ELISA  IHC-P  
                      • Slide 1
                      90010-T24-100
                      90010-T24-200
                      90010-T24-50
                      100 µg 
                      200 µg 
                      50 µg 
                      Add to Cart
                      Reactivity: Canine  
                      Application: ELISA  WB  
                      • Slide 1
                      70018-T48-200
                      70018-T48-100
                      70018-T48-50
                      200 µg 
                      100 µg 
                      50 µg 
                      Add to Cart
                      Reactivity: Canine  
                      Application: ELISA  
                        70018-RP01-400
                        70018-RP01-200
                        70018-RP01-100
                         
                        200 µg 
                        100 µg 
                        Add to Cart
                        Reactivity: Sus scrofa (Pig)  
                        Application: ELISA  
                          62003-T16-200
                          62003-T16-50
                          62003-T16-100
                          200 µg 
                          50 µg 
                          100 µg 
                          Add to Cart
                          Reactivity: Sus scrofa (Pig)  
                          Application: ELISA  
                            62003-RP01-400
                            62003-RP01-200
                            62003-RP01-100
                             
                            200 µg 
                            100 µg 
                            Add to Cart
                            Reactivity: Feline  
                            Application: ELISA  
                              67002-T16-100
                              67002-T16-50
                              67002-T16-200
                              100 µg 
                              50 µg 
                              200 µg 
                              Add to Cart
                              Reactivity: Feline  
                              Application: ELISA  
                                67002-RP01-400
                                67002-RP01-200
                                67002-RP01-100
                                 
                                200 µg 
                                100 µg 
                                Add to Cart
                                IL1B/IL-1B/IL-1 beta Background

                                Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).

                                Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

                                Human IL1B/IL-1B/IL-1 beta References
                              • Kim SH, et al. (2008) Association of -31TC and -511 CT polymorphisms in the interleukin 1 beta (IL1B) promoter in Korean keratoconus patients. Mol Vis. 14:2109-16.
                              • Wang ZC, et al. (2002) T helper 1-type immunity to trophoblast antigens in women with a history of recurrent pregnancy loss is associated with polymorphism of the IL1B promoter region. Genes Immun. 3(1): 38-42.
                              • Mattuzzi S, et al. (2007) Association of polymorphisms in the IL1B and IL2 genes with susceptibility and severity of systemic sclerosis. J Rheumatol. 34(5): 997-1004.
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                                Size / Price
                                Catalog: 10139-R012-50
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                                50 µg
                                100 µg
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                                Datasheet & Documentation

                                All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
                                Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"