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IL-1 beta / IL1B / IL1F2 Antibody, Rabbit PAb, Antigen Affinity Purified

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Human IL1B Antibody Product Information
Immunogen:Recombinant Human ILb protein (Catalog#10139-HNAE)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:Produced in rabbits immunized with purified, recombinant Human IL1B (rh IL1B; Catalog#10139-HNAE; NP_000567.1; Ala 117-Ser 269). IL1B specific IgG was purified by human IL1B affinity chromatography.
Human IL1B Antibody Usage Guide
Specificity:Human IL-1 beta / IL1B
Application:ELISA

ELISA: 0.5-1 μg/mL

This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human IL1b. The detection limit for Human IL1b is 0.00245 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other IL1B Antibody Products
Reactivity: Human  
Application: ELISA  
    10139-RP01-400
    10139-RP01-100
    10139-RP01-200
     
    100 µg 
    200 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      10139-R012-50
      10139-R012-100
      50 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  IHC-P  
      • Slide 1
      • Slide 1
      10139-M201-100
      10139-M201-50
      10139-M201-200
      100 µg 
      50 µg 
      200 µg 
      Add to Cart
      Reactivity: Mouse  
      Application: ELISA  
        50101-R020-50
        50101-R020-100
        50 µg 
        100 µg 
        Add to Cart
        Reactivity: Mouse  
        Application: ELISA  
          50101-R001-50
          50101-R001-100
          50 µg 
          100 µg 
          Add to Cart
          Reactivity: Mouse  
          Application: ELISA  
            50101-RP01-400
            50101-RP01-200
            50101-RP01-100
             
            200 µg 
            100 µg 
            Add to Cart
            Reactivity: Mouse  
            Application: ELISA  WB  
            • Slide 1
            50101-RP02-50
            50101-RP02-100
            50101-RP02-200
            50 µg 
            100 µg 
            200 µg 
            Add to Cart
            Reactivity: Mouse  
            Application: ELISA  WB  
            • Slide 1
            50101-T48-200
            50101-T48-100
            50101-T48-50
            200 µg 
            100 µg 
            50 µg 
            Add to Cart
            Reactivity: Rat  
            Application: ELISA  WB  
            • Slide 1
            80023-RP02-50
            80023-RP02-100
            80023-RP02-200
            50 µg 
            100 µg 
            200 µg 
            Add to Cart
            Reactivity: Rat  
            Application: ELISA  
              80023-RP01-100
              80023-RP01-200
              80023-RP01-400
              100 µg 
              200 µg 
               
              Add to Cart
              Reactivity: Rat  
              Application: ELISA  
                80023-R017-50
                80023-R017-100
                50 µg 
                100 µg 
                Add to Cart
                Reactivity: Cynomolgus  
                Application: ELISA  
                  90010-RP01-100
                  90010-RP01-400
                  90010-RP01-200
                  100 µg 
                   
                  200 µg 
                  Add to Cart
                  Reactivity: Cynomolgus  
                  Application: ELISA  IHC-P  
                  • Slide 1
                  90010-T24-100
                  90010-T24-200
                  90010-T24-50
                  100 µg 
                  200 µg 
                  50 µg 
                  Add to Cart
                  Reactivity: Canine  
                  Application: ELISA  WB  
                  • Slide 1
                  70018-T48-200
                  70018-T48-100
                  70018-T48-50
                  200 µg 
                  100 µg 
                  50 µg 
                  Add to Cart
                  Reactivity: Canine  
                  Application: ELISA  
                    70018-RP01-400
                    70018-RP01-200
                    70018-RP01-100
                     
                    200 µg 
                    100 µg 
                    Add to Cart
                    Reactivity: Sus scrofa (Pig)  
                    Application: ELISA  
                      62003-T16-200
                      62003-T16-50
                      62003-T16-100
                      200 µg 
                      50 µg 
                      100 µg 
                      Add to Cart
                      Reactivity: Sus scrofa (Pig)  
                      Application: ELISA  
                        62003-RP01-400
                        62003-RP01-200
                        62003-RP01-100
                         
                        200 µg 
                        100 µg 
                        Add to Cart
                        Reactivity: Feline  
                        Application: ELISA  
                          67002-T16-100
                          67002-T16-50
                          67002-T16-200
                          100 µg 
                          50 µg 
                          200 µg 
                          Add to Cart
                          Reactivity: Feline  
                          Application: ELISA  
                            67002-RP01-400
                            67002-RP01-200
                            67002-RP01-100
                             
                            200 µg 
                            100 µg 
                            Add to Cart
                            IL1B/IL-1B/IL-1 beta Background

                            Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).

                            Human IL1B/IL-1B/IL-1 beta References
                          • Kim SH, et al. (2008) Association of -31TC and -511 CT polymorphisms in the interleukin 1 beta (IL1B) promoter in Korean keratoconus patients. Mol Vis. 14:2109-16.
                          • Wang ZC, et al. (2002) T helper 1-type immunity to trophoblast antigens in women with a history of recurrent pregnancy loss is associated with polymorphism of the IL1B promoter region. Genes Immun. 3(1): 38-42.
                          • Mattuzzi S, et al. (2007) Association of polymorphisms in the IL1B and IL2 genes with susceptibility and severity of systemic sclerosis. J Rheumatol. 34(5): 997-1004.
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                            Catalog: 10139-RP02-200
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                            All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
                            Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"