All IGSF11 reagents are produced in house and quality controlled, including 1 IGSF11 Antibody, 1 IGSF11 Lysate, 1 IGSF11 Protein. All IGSF11 reagents are ready to use.
Recombinant IGSF11 proteins are expressed by HEK293 Cells with fusion tags as C-His.
IGSF11antibodies are validated with different applications, which are ELISA.
Immunoglobulin superfamily member 11(IGSF11) are expressed on the plasma membrane in the tesis and brain. These IGSF proteins undergo final modifications during capacitation and/or the acrosome reaction. IGSF proteins share significant homology with endothelial cell-selective adhesion molecule and coxsackievirus and adenovirus receptor, which mediates cell attachment and homotypic intercellular interactions. In clinical, the IGSF11 has been reported to over expressed in colorectal cancers and hepatocellular carcinomas as well as intestinal-type gastric cancers compared to their corresponding non- cancerous tissues. The IGSF11 has also been found expressed abundantly in testis and ovary and the IGSF11 can be used as a candidate of cancer-testis antigen.