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> IGFBP7 Protein & Antibody IGFBP7 Protein & Antibody
Insulin-like growth factor binding protein 7
IGFBP7 Products
IGFBP7 Protein, Recombinant
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| IGFBP7 | Human | IGFBP7 / IBP-7 Protein, Recombinant |
13100-H02H |
| IGFBP7 | Human | IGFBP7 / IBP-7 Protein, Recombinant | 13100-H07H |
| IGFBP7 | Human | IGFBP7 / IBP-7 Protein, Recombinant |
13100-H08H |
IGFBP7 Antibody
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human IGFBP7 | ELISA, IHC-P | IGFBP7 / IBP-7 Antibody (Antigen Affinity Purified) | 13100-RP02 |
| Human IGFBP7 | ELISA | IGFBP7 / IBP-7 Antibody | 13100-MM01 |
IGFBP7 cDNA Clone
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| IGFBP7 | Human | IGFBP7 / IBP-7 cDNA Clone / ORF Clone | HG13100-G |
IGFBP7 Related Areas
Cancer>>Growth Factor & Receptor>>IGF System>>IGFBP7
IGFBP7 Alternative Names
IGFBP7, AGM, FSTL2, IBP-7, IGFBP-7, IGFBP-7v, IGFBPRP1, MAC25, PSF, TAF [Homo sapiens]
Igfbp7, AGM, Fstl2, Mac25 [Mus musculus]
IGFBP7 Related Products
Protein Products
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| CCN3/NOV/IGFBP9 | Human | CCN3 / NOV / IGFBP9 Protein, Recombinant |
| CCN4/WISP1 | Human | CCN4 / WISP1 Protein, Recombinant |
| IGF1R/CD221 | Human | IGF1R / CD221 Protein, Recombinant |
| IGFBP3 | Human | IGFBP3 Protein, Recombinant |
| IGFBP4 | Human | IGFBP4 Protein, Recombinant |
| IGFBP4 | Mouse | IGFBP4 Protein, Recombinant |
| Insulin Receptor/CD220 | Human | Insulin Receptor / CD220 Protein, Recombinant |
| Insulin Receptor/CD220 | Human | Insulin Receptor / CD220 Protein, Recombinant |
Antibody Products
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! |
| Human CCN3/NOV/IGFBP9 |
WB, ELISA | CCN3 / NOV / IGFBP9 Antibody, Mouse Mab |
| Human CCN3/NOV/IGFBP9 |
WB, ELISA | CCN3 / NOV / IGFBP9 Rabbit PAb |
| Human IGF1R/CD221 |
WB | IGF1R / CD221 Mouse MAb |
| Human IGF1R/CD221 |
WB | IGF1R / CD221 Mouse MAb |
| Human IGF1R/CD221 |
ELISA | IGF1R / CD221 Mouse MAb |
| Human IGF1R/CD221 |
WB, ELISA | IGF1R / CD221 Rabbit MAb |
| Human IGF1R/CD221 |
ELISA | IGF1R / CD221 Rabbit PAb |
| Human IGF1R/CD221 |
WB, ELISA | IGF1R / CD221 Rabbit PAb (Antigen Affinity Purified) |
| Human IGFBP3 |
WB, ELISA | IGFBP3 Mouse MAb |
| Human IGFBP4 |
WB, ELISA | IGFBP4 Mouse MAb |
| IGFBP6 | Human | IGFBP6 Protein, Recombinant |
| IGFBP6 | Mouse | IGFBP6 Protein, Recombinant |
| Human Insulin Receptor/CD220 |
WB, ELISA | Insulin Receptor / CD220 Rabbit PAb |
cDNA Clone Products
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| CCN3/NOV/IGFBP9 | Human | Homo sapiens CCN3 / NOV / IGFBP9 cDNA Clone(NM_002514.3) |
| CCN3/NOV/IGFBP9 | Mouse | Mus musculus CCN3 / NOV / IGFBP9 cDNA Clone |
| CCN4/WISP1 | Human | Homo sapiens CCN4 / WISP1 cDNA Clone(NM_003882.2) |
| IGF1R /CD221 | Human | Homo sapiens IGF1R / CD221 cDNA Clone(NM_000875.3) |
| IGFBP3 | Human | Homo sapiens IGFBP3 cDNA Clone(NM_000598.4) |
| IGFBP4 | Human | Homo sapiens IGFBP4 cDNA Clone(NM_001552.2) |
| IGFBP4 | Mouse | Mus musculus IGFBP4 cDNA Clone |
| IGFBP5 | Human | Homo sapiens IGFBP5 cDNA Clone(NM_000599.3) |
| IGFBP5 | Mouse | Mus musculus IGFBP5 cDNA Clone |
| IGFBP6 | Human | Human IGFBP6 cDNA Clone / ORF Clone |
| IGFBP6 | Mouse | Mus musculus IGFBP6 cDNA Clone |
| CCN3/NOV/IGFBP9 | Human | Homo sapiens CCN3 / NOV / IGFBP9 cDNA Clone(NM_002514.3) |
| CCN3/NOV/IGFBP9 | Mouse | Mus musculus CCN3 / NOV / IGFBP9 cDNA Clone |
IGFBP7 Background
Insulin like growth factor binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are clearly distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have been shown to either inhibit or enhance the action of IGF, or act in an IGF-independent manner in the prostate. IGFBP7 could inhibit cell growth, decrease soft agar colony formation activity and induce apoptosis in RKO and SW620 cells. There is mounting evidence that the structure of the IGFBP proteins plays a key role in the regulation of IGF bioavailability, by modulating its molecular size, capillary membrane permeability, target tissue specificity, cell membrane adherence and IGF affinity.
IGFBP7 Related Studies
- Oh Y, et al. (1996) Synthesis and characterization of insulin-like growth factor-binding protein (IGFBP)-7. Recombinant human mac25 protein specifically binds IGF-I and -II. J Biol Chem. 271(48): 30322-5.
- Wilson EM, et al. (1997) Generation and characterization of an IGFBP-7 antibody: identification of 31kD IGFBP-7 in human biological fluids and Hs578T human breast cancer conditioned media. J Clin Endocrinol Metab. 82(4): 1301-3.
- Lin J, et al. (2007) Methylation patterns of IGFBP7 in colon cancer cell lines are associated with levels of gene expression. J Pathol. 212(1): 83-90.
