All IGFBP7 reagents are produced in house and quality controlled, including 9 IGFBP7 Antibody, 2 IGFBP7 ELISA, 26 IGFBP7 Gene, 2 IGFBP7 IPKit, 4 IGFBP7 Lysate, 4 IGFBP7 Protein, 1 IGFBP7 qPCR. All IGFBP7 reagents are ready to use.
Recombinant IGFBP7 proteins are expressed by HEK293 Cells with fusion tags as N-His, C-His, C-human IgG1-Fc.
IGFBP7antibodies are validated with different applications, which are WB, ELISA, IP, ELISA(Det), IHC-P, ELISA(Cap).
IGFBP7cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IGFBP7 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
IGFBP7ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Insulin like growth factor binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are clearly distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have been shown to either inhibit or enhance the action of IGF, or act in an IGF-independent manner in the prostate. IGFBP7 could inhibit cell growth, decrease soft agar colony formation activity and induce apoptosis in RKO and SW620 cells. There is mounting evidence that the structure of the IGFBP proteins plays a key role in the regulation of IGF bioavailability, by modulating its molecular size, capillary membrane permeability, target tissue specificity, cell membrane adherence and IGF affinity.