Anti-IGFBP7 Antibody

Cat: 13100-MM01
Contact us:
+86-400-890-9989
order@sinobiological.com
Distributors
All IGFBP7 Reagents
CRO Services
Product recommended

All IGFBP7 Reagents
Anti-IGFBP7 Antibody (Mouse Monoclonal antibody) General Information
Product name
Anti-IGFBP7 Antibody
Validated applications
ELISA,ELISA(Det)
Species reactivity
Reacts with: Human
Specificity
Human IGFBP7
No cross-reactivity in ELISA with Human IGFBP3 Human IGFBP4 Human IGFBP6 Human cell lysate (293 cell line)
Immunogen
Recombinant Human IGFBP7 protein (Catalog#13100-H08H)
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IGFBP7 (rh IGFBP7; Catalog#13100-H08H; Q16270; Met 1-Leu 282). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Source
Monoclonal Mouse IgG1 Clone #01
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-IGFBP7 Antibody (Mouse Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  
ELISA(Det) 1:1000-1:10000 This antibody will detect Human IGFBP7 in ELISA pair set (Catalog: # SEK13100). In a sandwich ELISA, it can be used as detection antibody when paired with (Catalog: # 13100-MM12).

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-IGFBP7 Antibody Alternative Names
Anti-AGM Antibody;Anti-FSTL2 Antibody;Anti-IBP-7 Antibody;Anti-IGFBP-7 Antibody;Anti-IGFBP-7v Antibody;Anti-IGFBPRP1 Antibody;Anti-MAC25 Antibody;Anti-PSF Antibody;Anti-RAMSVPS Antibody;Anti-TAF Antibody
IGFBP7 Background Information

Insulin like growth factor binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are clearly distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have been shown to either inhibit or enhance the action of IGF, or act in an IGF-independent manner in the prostate. IGFBP7 could inhibit cell growth, decrease soft agar colony formation activity and induce apoptosis in RKO and SW620 cells. There is mounting evidence that the structure of the IGFBP proteins plays a key role in the regulation of IGF bioavailability, by modulating its molecular size, capillary membrane permeability, target tissue specificity, cell membrane adherence and IGF affinity.

Full Name
insulin-like growth factor binding protein 7
References
  • Oh Y, et al. (1996) Synthesis and characterization of insulin-like growth factor-binding protein (IGFBP)-7. Recombinant human mac25 protein specifically binds IGF-I and -II. J Biol Chem. 271(48): 30322-5.
  • Wilson EM, et al. (1997) Generation and characterization of an IGFBP-7 antibody: identification of 31kD IGFBP-7 in human biological fluids and Hs578T human breast cancer conditioned media. J Clin Endocrinol Metab. 82(4): 1301-3.
  • Lin J, et al. (2007) Methylation patterns of IGFBP7 in colon cancer cell lines are associated with levels of gene expression. J Pathol. 212(1): 83-90.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-IGFBP7 Antibody Rabbit Polyclonal WB,ELISA,IHC-P 13100-T56
    Anti-IGFBP7 Antibody Rabbit Polyclonal WB,ELISA,IHC-P 13100-RP02
    Anti-IGFBP7 Antibody Mouse Monoclonal ELISA(Cap) 13100-MM12
    Anti-IGFBP7 Antibody Rabbit Monoclonal WB,IP 13100-R065
    Anti-IGFBP7 Antibody Rabbit Polyclonal WB,ELISA,IP 13100-T52
    Anti-IGFBP7 Antibody Rabbit Monoclonal IHC-P 13100-R115
    Anti-IGFBP7 Antibody Rabbit Polyclonal ELISA 13100-RP01
    Anti-IGFBP7 Antibody Rabbit Monoclonal ELISA 13100-R003
    info info
    添加购物车成功! 添加购物车失败!