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>Human Cell Expressed
>Human IFN omega 1 / IFNW1 Protein (His Tag)
|Catalog||Size (Price)||Quantity||In Stock||Operation|
Interferon, omega 1 Protein Datasheet
IFNW1 Protein Price Inquiry ( Available Sizes )
IFNW1 Protein Product Information
A DNA sequence encoding the human IFNW1 (P05000) (Met1-Ser195) was expressed with a polyhistidine tag at the C-terminus.
|Expression Host:||Human Cells|
IFNW1 Protein QC Testing
|Purity:||> 95% as determined by SDS-PAGE||SDS-PAGE:
|Measured in antiviral assays using WISH human amnion cells infected with vesicular stomatitis virus(VSV).
The ED50 for this effect is typically 2-8 pg/mL.
|Endotoxin:||< 1.0 EU per μg of the protein as determined by the LAL method|
|Stability:||Samples are stable for up to twelve months from date of receipt at -70℃|
|Predicted N terminal:||Leu 22|
The recombinant human IFNW1 consists of 185 amino acids and predicts a molecular mass of 21.6 KDa. It migrates as an approximately 22 KDa band in SDS-PAGE under reducing conditions.
|Formulation:||Lyophilized from sterile PBS, pH 7.4.
IFNW1 Protein Usage Guide
|Storage:||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution:||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
IFNW1 Protein Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|IFN omega/IFNW||Human||IFN omega/IFNW/Fc Protein, Recombinant||10353-H01H|
|IFN omega/IFNW||Human||IFNW1 Protein, Recombinant||10353-H08H|
IFNW1 Protein Description
IFNs are a large family of proteins having antiviral, antiproliferative, and immunomodulatory effects, and are divided into two major classes, type I and type I I, on the basis of differences in receptor binding and nucleotide sequence. Type I IFNs consist of IFN α, β, τ, and ω and bind to the type I IFN receptor, whereas IFN-γ is the only type I I IFN and is specific for the type I I IFN receptor. Human IFN-ω, was identified by three independent groups in 1985 and is structurally related to IFN-α and -β. Both human IFN-ω and IFN-α are produced by virally induced leukocytes and have similar antiviral activities on human cell lines, and a sizeable proportion (at least 10%) of the total antiviral activity of leukocyte IFN is contributed by IFN-ωl. In addition, it was reported that IFN-ω could inhibit the growth of human tumors in vivo.
- Holly M Horton. et al., 1999, Cancer Research. 59: 4064-8.
- Rudolf Hauptmann Peter Swetly. 1985, Nucleic acids Research. 13 (13): 4739-49.
- Günther R Adolf. et al., 1990, The Journal of Biological Chemistry. 265 (16): 9290-5.
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