|Datasheet||Specific References||Reviews||Related Products||Protocols|
|ORF Clone of Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) interferon gamma receptor 1 DNA.|
|Identical with NM_001032905.1 [ Macaca mulatta (Rhesus monkey) ]: 1050 C/T not causing the amino acid variation. Please check the sequence information before order.|
|Whatman FTA elute card (Cat: WB120410) contains 5-10 μg of plasmid.|
|The Whatman FTA elute card can be stored at room temperature for three months under dry condition.|
The pGEM-T is 3kb in length, and contains the amplicin resistance gene, conferring selection of the plasmid in E. coli, and the ori site which is the bacterial origin of replication. The plasmid has multiple cloning sites as shown below. The coding sequence was inserted by TA cloning. Many E. coli strains are suitable for the propagation of this vector including JM109, DH5α and TOP10.
The coding sequence can be easily obtained by digesting the vector with proper restriction enzyme(s). The coding sequence can also be amplified by PCR with M13 primers, or primer pair SP6 and T7.
|Cynomolgus monkey IFNGR1 Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged||CG90207-G-F|
|Cynomolgus monkey IFNGR1 Gene cDNA Clone (full-length ORF Clone), expression ready, His-tagged||CG90207-G-H|
|Cynomolgus monkey IFNGR1 Gene cDNA Clone (full-length ORF Clone), expression ready, Myc-tagged||CG90207-G-M|
|Cynomolgus monkey IFNGR1 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged||CG90207-G-N|
|Cynomolgus monkey IFNGR1 Gene cDNA Clone (full-length ORF Clone), expression ready, HA-tagged||CG90207-G-Y|
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The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD119 (cluster of differentiation 119), also known as IFNGR1 ( interferon gamma receptor 1), is part of the heterodimeric gamma interferon receptor which consists of IFNGR1 (CD119) and IFNGR2. The IFNGR1 gene encodes the ligand-binding chain (alpha) of the interteron receptor while IFNGR gene encodes the non-ligand binding partner. The ability of the interferon-γ was achieved through binding to the interferon receptor CD119. After binding, the products of activated T-lymphocytes interferon-γ exerts antiviral activity, growth inhibitory effect, and several immune- regulatory activities on a variety of cell types.