IFNGR1 cDNA ORF Clone in Cloning Vector, Rhesus

Cat: CG90207-G
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IFNGR1 cDNA ORF Clone in Cloning Vector, Rhesus General Information
Gene
Species
Rhesus
NCBI Ref Seq
RefSeq ORF Size
1467 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence except for the point mutations: 1050C/T not causing the amino acid variation. Please check the sequence information before order.
Description
Full length Clone DNA of Rhesus interferon gamma receptor 1.
Plasmid
Vector
pGEM-T Vector
Sequencing Primers
SP6 and T7 or M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Ampicillin
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.
IFNGR1 cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

IFNGR1 Background Information

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD119 (cluster of differentiation 119), also known as IFNGR1 ( interferon gamma receptor 1), is part of the heterodimeric gamma interferon receptor which consists of IFNGR1 (CD119) and IFNGR2. The IFNGR1 gene encodes the ligand-binding chain (alpha) of the interteron receptor while IFNGR gene encodes the non-ligand binding partner. The ability of the interferon-γ was achieved through binding to the interferon receptor CD119. After binding, the products of activated T-lymphocytes interferon-γ exerts antiviral activity, growth inhibitory effect, and several immune- regulatory activities on a variety of cell types.

Full Name
interferon gamma receptor 1
References
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12
  • Novick D, et al. (1987) The human interferon-gamma receptor. The journal of biological chemistry. 262 (18): 8483-7
  • IFNGR1 cDNA ORF Clone, Rhesus, Related Products

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    IFNGR1 cDNA ORF Clone, Rhesus, N-His tag CG90207-NH
    IFNGR1 cDNA ORF Clone, Rhesus, C-HA tag CG90207-CY
    IFNGR1 cDNA ORF Clone, Rhesus, N-HA tag CG90207-NY
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    IFNGR1 cDNA ORF Clone in Cloning Vector, Rat RG80328-G
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    IFNGR1 cDNA ORF Clone, Human, Related Products

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