IFNGR1 Protein & Antibody (CD119)

Interferon Gamma Receptor 1 (Cluster of Differentiation 119)

IFNGR Products

IFNGR1 Protein, Recombinant

Molecule	Species	Description	Cat. No
IFNGR1/CD119	Human	IFNGR1/CD119/Fc Protein, Recombinant	10338-H03H
IFNGR1/CD119	Human	IFNGR1/CD119 Protein, Recombinant	10338-H08H
IFNGR1/CD119	Mouse	IFNGR1 / CD119 Protein, Recombinant	50705-M02H
IFNGR1/CD119	Mouse	IFNGR1 / CD119 Protein, Recombinant	50705-M08H

IFNGR1 Antibody

Molecule	Application	Description	Cat. No
Human IFNGR1/CD119	WB, ELISA	IFNGR1 / CD119 Antibody	10338-MM10
Human IFNGR1/CD119	WB, ELISA	IFNGR1/CD119 Antibody, Rabbit MAb	10338-R010
Human IFNGR1/CD119	WB, ELISA	Rabbit Polyclonal Antibody	10338-RP01
Human IFNGR1/CD119	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10338-RP02

IFNGR1 cDNA Clone

Molecule	Species	Description	Cat. No
IFNGR1/CD119	Human	Homo sapiens IFNGR1/CD119 cDNA Clone(NM_000416.2)	HG10338-M
IFNGR1/CD119	Mouse	IFNGR1/CD119 cDNA Clone / ORF Clone	MG50705-M
IFNGR1/CD119	Rat	IFNGR1 cDNA Clone / ORF Clone	RG80328-G

IFNGR1 Related Areas

Cancer>>Angiogenesis>>Cytokines/Chemokines in Angiogenesis>>IFNGR1/CD119

Immunology>>Cytokine & Receptor>>Interleukin & Receptor >>IL-10/Interferon Family>>IFNGR1/CD119

Immunology>>Cluster of Differentiation>>B Cell CD Antigen>>IFNGR1/CD119

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Macrophage Markers>>IFNGR1/CD119

Immunology>>Cluster of Differentiation>>T Cell CD Antigen>>Helper T Cells>>IFNGR1/CD119

IFNGR1 Alternative Names

IFNGR1, CD119, IFNGR, RP3-503F13.3, FLJ45734 [Homo sapiens]

Ifngr1, CD119, Ifngr, IFN-gammaR, Ifgr, Nktar [Mus musculus]

IFNGR1 Background

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD119 (cluster of differentiation 119), also known as IFNGR1 ( interferon gamma receptor 1), is part of the heterodimeric gamma interferon receptor which consists of IFNGR1 (CD119) and IFNGR2. The IFNGR1 gene encodes the ligand-binding chain (alpha) of the interteron receptor while IFNGR gene encodes the non-ligand binding partner. The ability of the interferon-γ was achieved through binding to the interferon receptor CD119. After binding, the products of activated T-lymphocytes interferon-γ exerts antiviral activity, growth inhibitory effect, and several immune- regulatory activities on a variety of cell types.

IFNGR1 Related Studies

1. Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
2. Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125–35.
3. Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12
4. Novick D, et al. (1987) The human interferon-γ receptor. The journal of biological chemistry. 262 (18): 8483-7