Anti-IFNGR1 Antibody

Cat: 10338-R010
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Anti-IFNGR1 Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-IFNGR1 Antibody
Validated applications
WB,ELISA
Species reactivity
Reacts with: Human
Specificity
Human IFNGR1
No cross-reactivity in ELISA with Human IL10RB / CRFB4
Immunogen
Recombinant Human CD119 protein (Catalog#10338-H08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human IFNGR1 / CD119 (rh IFNGR1; Catalog#10338-H08H; NP_000407.1; Met 1-Gly 245).
Source
Monoclonal Rabbit IgG Clone #10
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-IFNGR1 Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
WB 1:500-1:1000  
ELISA 1:25000-1:50000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-IFNGR1 Antibody (Rabbit Monoclonal antibody) Images
Human IFNGR1/CD119 Western blot (WB) 13189

Anti-IFNGR1 rabbit monoclonal antibody at 1:500 dilution

Lane A: MCF7 Whole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:54 kDa

Observed band size:54 kDa

Anti-IFNGR1 Antibody Alternative Names
Anti-CD119 Antibody;Anti-IFNGR Antibody;Anti-IMD27A Antibody;Anti-IMD27B Antibody
IFNGR1 Background Information

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD119 (cluster of differentiation 119), also known as IFNGR1 ( interferon gamma receptor 1), is part of the heterodimeric gamma interferon receptor which consists of IFNGR1 (CD119) and IFNGR2. The IFNGR1 gene encodes the ligand-binding chain (alpha) of the interteron receptor while IFNGR gene encodes the non-ligand binding partner. The ability of the interferon-γ was achieved through binding to the interferon receptor CD119. After binding, the products of activated T-lymphocytes interferon-γ exerts antiviral activity, growth inhibitory effect, and several immune- regulatory activities on a variety of cell types.

Full Name
interferon gamma receptor 1
References
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12
  • Novick D, et al. (1987) The human interferon-gamma receptor. The journal of biological chemistry. 262 (18): 8483-7
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-IFNGR1 Antibody Rabbit Polyclonal ELISA 50705-T16
    Anti-IFNGR1 Antibody Rabbit Monoclonal ELISA,ELISA(Det) 50705-R074
    Anti-IFNGR1 Antibody (FITC) Rabbit Monoclonal FCM 50705-R062-F
    Anti-IFNGR1 Antibody Rabbit Monoclonal ELISA(Cap),FCM,ICC/IF,IF 50705-R062
    Anti-IFNGR1 Antibody (APC) Rabbit Monoclonal FCM 50705-R062-A
    Anti-IFNGR1 Antibody (PE) Rabbit Monoclonal FCM 50705-R062-P
    Anti-IFNGR1 Antibody Rabbit Polyclonal ELISA 10338-RP01
    Anti-IFNGR1 Antibody Mouse Monoclonal ELISA 10338-MM10
    Anti-IFNGR1 Antibody (APC) Mouse Monoclonal FCM 10338-MM05-A
    Anti-IFNGR1 Antibody Rabbit Polyclonal ELISA 10338-RP02
    Anti-IFNGR1 Antibody (PE) Mouse Monoclonal FCM 10338-MM05-P
    Anti-IFNGR1 Antibody Mouse Monoclonal FCM 10338-MM05
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