All interferon-alpha reagents are produced in house and quality controlled, including 9 interferon-alpha Antibody, 2 interferon-alpha ELISA, 39 interferon-alpha Gene, 2 interferon-alpha IPKit, 4 interferon-alpha Lysate, 7 interferon-alpha Protein, 2 interferon-alpha qPCR. All interferon-alpha reagents are ready to use.
Recombinant interferon-alpha proteins are expressed by HEK293 Cells, Yeast with fusion tags as C-human IgG1-Fc, C-His, N-human IgG1-Fc.
interferon-alphaantibodies are validated with different applications, which are WB, ELISA, IHC-P, IP, ELISA(Cap).
interferon-alphacDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each interferon-alpha of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
interferon-alphaELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Interferon, alpha 5 (IFNA5) belongs to the alpha/beta interferon family. IFNA5 is the only IFNA subtype detected in normal liver, while a mixture of subtypes is observed in the liver tissue of patients with chronic hepatitis C. Interferons are produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytokine to be produced by recombinant DNA technology, has emerged as an important regulator of growth and differentiation, affecting cellular communication and signal transduction pathways as well as immunological control. Originally discovered as an antiviral substance, the efficacy of IFN-alpha in malignant, viral, immunological, angiogenic, inflammatory, and fibrotic diseases suggests a spectrum of interrelated pathophysiologies. IFN-alpha emerged as a prototypic tumor suppressor protein that represses the clinical tumorigenic phenotype in some malignancies capable of differentiation.