All IFNA4 reagents are produced in house and quality controlled, including 4 IFNA4 Antibody, 52 IFNA4 Gene, 6 IFNA4 Lysate, 7 IFNA4 Protein, 3 IFNA4 qPCR. All IFNA4 reagents are ready to use.
Recombinant IFNA4 proteins are expressed by HEK293 Cells, Baculovirus-Insect Cells, Yeast with fusion tags as N-human IgG1-Fc, C-His, C-mouse IgG1-Fc.
IFNA4antibodies are validated with different applications, which are ELISA.
IFNA4cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IFNA4 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Interferon, alpha 4 (IFNA4) belongs to the alpha/beta interferon family. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410 and can be distinguished by selective restriction enzyme analysis. Interferons are produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytokine to be produced by recombinant DNA technology, has emerged as an important regulator of growth and differentiation, affecting cellular communication and signal transduction pathways as well as immunological control. Originally discovered as an antiviral substance, the efficacy of IFN-alpha in malignant, viral, immunological, angiogenic, inflammatory, and fibrotic diseases suggests a spectrum of interrelated pathophysiologies. IFN-alpha emerged as a prototypic tumor suppressor protein that represses the clinical tumorigenic phenotype in some malignancies capable of differentiation.