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> IFN gamma Protein & Antibody (IFNG) IFN gamma Protein & Antibody (IFNG)
Interferon gamma
IFN gamma Products
IFN gamma Protein, Recombinant
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| IFN gamma/IFNG | Human | IFN gamma/IFNG Protein, Recombinant |
11725-HNAS |
| IFN gamma/IFNG | Mouse | IFN gamma/IFNG Protein, Recombinant | 50709-M02H |
| IFN gamma/IFNG | Mouse | IFN gamma/IFNG Protein, Recombinant | 50709-M08H |
| IFN gamma/IFNG | Rat | IFNG / Interferon Gamma Protein, Recombinant | 80234-R02H |
IFN gamma Antibody
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human IFN gamma/IFNG |
WB, ELISA | IFN gamma/IFNG Antibody, Rabbit MAb | 11725-R121 |
| Human IFN gamma/IFNG |
WB, ELISA | IFN gamma/IFNG Antibody, Rabbit PAb | 11725-RP01 |
| Human IFN gamma/IFNG |
WB, ELISA | IFN gamma/IFNG Antibody, Rabbit PAb (Antigen Affinity Purified) | 11725-RP02 |
IFN gamma cDNA Clone
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| IFN gamma/IFNG | Human | Human IFNG Gene cDNA Clone / ORF Clone | HG14064-G |
| IFN gamma/IFNG | Mouse | IFN gamma/IFNG cDNA Clone / ORF Clone | MG50709-M |
| IFN gamma/IFNG | Ferret | IFNG cDNA Clone / ORF Clone | FG60007-G |
| IFN gamma/IFNG | Rat | IFNG cDNA Clone / ORF Clone | RG80234-G |
| IFN gamma/IFNG | Cynomolgus | IFN gamma/IFNG cDNA Clone / ORF Clone | CG90008-M |
IFN gamma Related Areas
Immunology>>Cytokine & Receptor>>Interleukin & Receptor>>IL-10/Interferon Family>>IFN gamma/IFNG
IFN gamma Alternative Names
IFN gamma, IFNG, IFG, IFI, immune interferon, interferon gamma [Homo sapiens]
IFN gamma, Ifng, IFN-g, Ifg, gamma interferon [Mus musculus]
IFN gamma Background
IFN gamma, also known as IFNG, is a secreted protein which belongs to the type I I interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. The IFNG monomer consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region. IFN gamma is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN gamma expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNG also promotes NK cell activity.
IFN gamma Related Studies
- Gray P W, et al. (1982) Structure of the human immune interferon gene. Nature. 298: 859-63.
- Taya Y, et al. (1982) Cloning and structure of the human immune interferon-gamma chromosomal gene. EMBO J. 1: 953-8.
- Goshima N, et al. (2008) Human protein factory for converting the transcriptome into an in vitro-expressed proteome. Nomura N Nat Methods. 5: 1011-7.
- Thiel DJ, et al. (2000) Observation of an unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex. Structure. 8 (9): 927-36.
- Naylor SL, et al. (1983) Human immune interferon gene is located on chromosome 12. J Exp Med. 157 (3): 1020-7.
- Schoenborn JR, et al. (2007) Regulation of interferon-gamma during innate and adaptive immune responses. Adv Immunol. 96: 41-101.
Interferons
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