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Product Catalog
> IFN beta Protein & Antibody (IFNB) IFN beta Protein & Antibody (IFNB)
Interferon beta
IFN beta / IFNB Products
IFN beta / IFNB Protein, Recombinant
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| IFN beta/IFNB | Human | IFN beta / IFNB / Fc Protein, Recombinant |
10704-H02H |
| IFN beta/IFNB | Human | IFN beta / IFNB Protein, Recombinant |
10704-HNAC |
| IFN beta/IFNB | Mouse | IFNB1 / IFN beta / Interferon beta Protein, Recombinant | 50708-M02H |
IFN beta / IFNB Antibody
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human IFN beta/IFNB |
WB, ELISA | IFN beta / IFNB Mouse MAb | 10704-MM01 |
| Human IFN beta/IFNB |
WB, ELISA | IFN beta / IFNB Antibody (Antigen Affinity Purified) | 10704-RP02 |
IFNB1 cDNA Clone
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| IFNB1 | Mouse | IFN beta / IFNB1 cDNA Clone / ORF Clone | MG50708-M |
IFN beta / IFNB Related Areas
Cancer>>Angiogenesis>>Cytokines/Chemokines in Angiogenesis>>IFN beta/IFNB
Immunology>>Cytokine & Receptor>>Interleukin & Receptor >>IL-10/Interferon Family>>IFN beta/IFNB
IFN beta / IFNB Alternative Names
IFN beta, IFNB [Homo sapiens]
IFN beta, Ifnb1, RP23-19G2.2, IFNB, Ifb [Mus musculus]
IFN beta / IFNB Background
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily, and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, parasites and tumor cells. Interferon-beta (IFN beta) is an extra-cellular protein mediator of host defense and homeostasis. IFN beta has well-established direct antiviral, antiproliferative and immunomodulatory properties. Recombinant IFN beta is approved for the treatment of relapsing-remitting multiple sclerosis. The recombinant IFN beta protein has the theoretical potential to either treat or cause autoimmune neuromuscular disorders by altering the complicated and delicate balances within the immune system networks. It is the most widely prescribed disease-modifying therapy for multiple sclerosis (MS). Large-scale clinical trials have established the clinical efficacy of IFN beta in reducing relapses and slowing disease progression in relapsing-remitting MS. IFN beta therapy was shown to be comparably beneficial for opticospinal MS (OSMS) and conventional MS in Japanese. IFN beta is effective in reducing relapses in secondary progressive MS and may have a modest effect in slowing disability progression. In addition to the common antiviral activity, IFN beta also induces increased production of the p53 gene product which promotes apoptosis, and thus has therapeutic effect against certain cancers. The role of IFN-beta in bone metabolism could warrant its systematic evaluation as a potential adjunct to therapeutic regimens of osteolytic diseases. Furthermore, IFN beta might play a beneficial role in the development of a chronic progressive CNS inflammation.
IFN beta / IFNB Related Studies
- Kohriyama T, et al. (2008) Interferon-beta treatment for multiple sclerosis and predictors of response. Nippon Rinsho. 66(6): 1119-26.
- Stübgen JP. (2009) Recombinant interferon-beta therapy and neuromuscular disorders. J Neuroimmunol. 212(1-2): 132-41.
- Abraham AK, et al. (2009) Mechanisms of interferon-beta effects on bone homeostasis. Biochem Pharmacol. 77(12): 1757-62.
IFN beta related areas, pathways, and other information
Interferons
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