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IFN-alpha / IFNA1 / IFN  Protein, Antibody, ELISA Kit, cDNA Clone

Expression host: Yeast  
  • Slide 1
12341-H08Y-100
12341-H08Y-20
100 µg 
20 µg 
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Expression host: Yeast  
  • Slide 1
50524-M08Y-100
50524-M08Y-20
100 µg 
20 µg 
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Expression host: Human Cells  
  • Slide 1
80174-R02H-100
80174-R02H-20
100 µg 
20 µg 
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Description: Active  
Expression host: Human Cells  
  • Slide 1
80174-R08H-5
80174-R08H-100
80174-R08H-20
5 µg 
100 µg 
20 µg 
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IFN-alpha / IFNA1 / IFN Related Pathways

IFN-alpha / IFNA1 / IFN Related Protein, Antibody, cDNA Gene, and ELISA Kits

IFN-alpha / IFNA1 / IFN Related Protein, Antibody, cDNA Gene, and ELISA Kits

IFN-alpha / IFNA1 / IFN Summary & Protein Information

IFN-alpha / IFNA1 / IFN Background

Gene Summary: The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted.
General information above from NCBI
Subcellular location: Secreted.
Sequence similarity: Belongs to the alpha/beta interferon family.
General information above from UniProt

IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs can activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they also increase the ability of uninfected host cells to resist new infection by virus.Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon is produced by mitogen- or antigen-stimulated T lymphocytes. IFNA1 is produced by macrophages and has antiviral activities.

IFN-alpha / IFNA1 / IFN Alternative Name

IFL,IFN,IFNA@,IFNA13,IFN-ALPHA,IFN-alphaD, [homo-sapiens]
IFL,IFN,IFNA@,IFN-ALPHA,IFN-alpha 1b,IFN-alpha-1/13,IFN-alphaD,interferon alpha 1b,interferon alpha-1/13,interferon alpha-D,interferon-alpha1,leIF D,MGC138207,MGC138505,MGC138507,IFNA13, [human]
Ifa1,IFN-alpha-1,interferon alpha family gene 1,interferon alpha-1,RP23-360M23.1, [mouse]
Ifa1, [mus-musculus]

IFN-alpha / IFNA1 / IFN Related Studies

  • Takayama I, et al. (2012) The nucleocapsid protein of measles virus blocks host interferon response. Virology. 424(1):45-55.
  • Vairo D, et al. (2011) Severe impairment of IFN-? and IFN-? responses in cells of a patient with a novel STAT1 splicing mutation. Blood. 118(7):1806-17.
  • Bhattacharya S, et al. (2011) Bcr-abl signals to desensitize chronic myeloid leukemia cells to IFN? via accelerating the degradation of its receptor. Blood. 118(15):4179-87.
  • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"