Anti-ICAM-2 Antibody

Cat: 10332-RP02
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All ICAM-2 Reagents
Anti-ICAM-2 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-ICAM-2 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human ICAM-2
Recombinant Human ICAM-2 / CD102 protein (Catalog#10332-H08H)
Produced in rabbits immunized with purified, recombinant Human ICAM-2 / CD102 (rh ICAM-2 / CD102; Catalog#10332-H08H; NP_777596.2; Met 1-Gln 223). ICAM-2 / CD102 specific IgG was purified by Human ICAM-2 / CD102 affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-ICAM-2 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
WB 1:500-1:1000  
ELISA 1:25000-1:50000  
IP 1-2 μL/mg of lysate  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-ICAM-2 Antibody (Rabbit Polyclonal antibody) Images
Human ICAM-2/CD102 Immunoprecipitation(IP) 6160

ICAM2 was immunoprecipitated using:

Lane A:0.5 mg Hela Whole Cell Lysate

0.5 µL anti-ICAM2 rabbit polyclonal antibody and 60 μg of Immunomagnetic beads Protein G.

Primary antibody:

Anti-ICAM2 rabbit polyclonal antibody,at 1:500 dilution

Secondary antibody:

Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution

Developed using the odssey technique.

Performed under reducing conditions.

Predicted band size: 31 kDa

Observed band size: 31 kDa

Human ICAM-2/CD102 Western blot (WB) 13186

Anti-ICAM2 rabbit polyclonal antibody at 1:500 dilution

Lane A: HL60 Membrane Lysate

Lysates/proteins at 20 μg per lane.


Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:31 kDa

Observed band size:47 kDa

Anti-ICAM-2 Antibody Alternative Names
Anti-CD102 Antibody
ICAM-2 Background Information

Intercellular adhesion molecule 2 (ICAM-2, CD102), belongs to the ICAM family consisting of three members identified as ligands for integrin receptors. It is a type I transmembrane glycoprotein with two Ig-like C2-type domains, and binds to the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). As a second ligand of leukocyte function-associated antigen-1, ICAM-2 functions as a costimulatory molecule for effector cells. ICAM-2 is mainly expressed on vascular endothelial and hematopoietic cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocytewith other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.

Full Name
intercellular adhesion molecule 2
  • Weber KS, et al. (2004) Sialylation of ICAM-2 on platelets impairs adhesion of leukocytes via LFA-1 and DC-SIGN. Inflammation. 28(4): 177-88.
  • Tanaka H, et al. (2004) ICAM-2 gene therapy for peritoneal dissemination of scirrhous gastric carcinoma. Clin Cancer Res. 10(14): 4885-92.
  • Younis AI, et al. (2005) Intercellular adhesion molecule-2 (ICAM-2) in experimental trichinosis. J Egypt Soc Parasitol. 35(3): 1019-26.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-ICAM-2 Antibody Rabbit Monoclonal WB,ELISA 10332-R041
    Anti-ICAM-2 Antibody Rabbit Monoclonal WB 10332-R055
    Anti-ICAM-2 Antibody Mouse Monoclonal ELISA 10332-MM01
    Anti-ICAM-2 Antibody Rabbit Monoclonal ELISA(Det) 10332-R015
    Anti-ICAM-2 Antibody Mouse Monoclonal IHC-P 10332-MM06
    Anti-ICAM-2 Antibody Rabbit Monoclonal WB 10332-R033
    Anti-ICAM-2 Antibody Rabbit Polyclonal ELISA 10332-RP01
    Anti-ICAM-2 Antibody Rabbit Monoclonal ELISA(Cap) 10332-R022
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