Anti-ICAM-1 Antibody (PE)

Cat: 80022-R037-P
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All ICAM-1 Reagents
CRO Services
Product recommended

All ICAM-1 Reagents
Anti-ICAM-1 Antibody (PE) (Rabbit Monoclonal antibody) General Information
Product name
Anti-ICAM-1 Antibody (PE)
Validated applications
FCM
Species reactivity
Reacts with: Rat
Specificity
Rat ICAM-1
Immunogen
Recombinant Rat ICAM-1 / CD54 protein (Catalog#80022-R08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Rat ICAM-1 / CD54 (rR ICAM-1 / CD54; Catalog#80022-R08H; Q00238-1; Met1-Thr493) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Source
Monoclonal Rabbit IgG Clone #037
Purification
Protein A
Formulation
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Conjugate
PE
Concentration
2 μl/Test, 0.1 mg/ml
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Anti-ICAM-1 Antibody (PE) (Rabbit Monoclonal antibody) Validated Applications

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-ICAM-1 Antibody (PE) (Rabbit Monoclonal antibody) Images
Rat ICAM-1/CD54 Flow Cytometry (FC) 4829
Analysis of Rat ICAM1(CD54) expression on spleen lymphocytes. Crossreactivity on both rat and mouse splenocytes is observed. The histogram were derived from the gated events based on light scattering characteristics of lymphocytes.
ICAM-1 Background Information

Intercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and in animal models of atherosclerosis. Additionally, ICAM-1 has been implicated in the progression of autoimmune diseases. ICAM-1 is a ligand for LFA-1(integrin). When activated, leukocytes bind to endothelial cells via ICAM-1/LFA-1 interaction and then transmigrate into tissues. Presence with heavy glycosylation and other structural characteristics, ICAM-1 possesses binding sites for a number of immune-associated ligands and serves as the binding site for entry of the major group of human Rhinovirus (HRV) into various cell types. ICAM-1 also becomes known for its affinity for Plasmodium falciparum-infected erythrocytes (PFIE), providing more of a role in infectious disease. Previous studies have shown that ICAM-1 is involved in inflammatory reactions and that a defect in ICAM-1 gene inhibits allergic contact hypersensitivity.

Full Name
intercellular adhesion molecule 1
Research Areas
References
  • Xu H, et al. (2001) The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph node. Eur J Immunol. 31(10): 3085-93.
  • Terol MJ, et al. (2003) Soluble intercellular adhesion molecule-1 (s-ICAM-1/s-CD54) in diffuse large B-cell lymphoma: association with clinical characteristics and outcome. Ann Oncol. 14(3): 467-74.
  • Mendez MP, et al. (2006) Shedding of soluble ICAM-1 into the alveolar space in murine models of acute lung injury. Am J Physiol Lung Cell Mol Physiol. 290(5): L962-70.
  • Lawson C, et al. (2009) ICAM-1 signaling in endothelial cells. Pharmacol Rep. 61(1): 22-32.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-ICAM-1 Antibody Rabbit Polyclonal ELISA,IP 80022-RP02
    Anti-ICAM-1 Antibody Mouse Monoclonal ELISA 80022-MM11
    Anti-ICAM-1 Antibody Rabbit Monoclonal ELISA,ELISA(Det) 80022-R112
    Anti-ICAM-1 Antibody Mouse Monoclonal IHC-P 80022-MM15
    Anti-ICAM-1 Antibody Rabbit Polyclonal ELISA 80022-RP01
    Anti-ICAM-1 Antibody Rabbit Monoclonal ELISA 80022-R143
    Anti-ICAM-1 Antibody Rabbit Monoclonal IHC-P 80022-R003
    Anti-ICAM-1 Antibody (FITC) Rabbit Monoclonal FCM 80022-R037-F
    Anti-ICAM-1 Antibody Rabbit Monoclonal ELISA(Cap),FCM,ICC/IF,IF 80022-R037
    Anti-ICAM-1 Antibody (APC) Rabbit Monoclonal FCM 80022-R037-A
    Anti-ICAM-1 Antibody Rabbit Polyclonal WB,ELISA,IHC-P,IP 80022-T60
    Anti-ICAM-1 Antibody Rabbit Polyclonal ELISA,IHC-P 50440-RP02
    Anti-ICAM-1 Antibody Rabbit Polyclonal ELISA,IHC-P 50440-T24
    Anti-ICAM-1 Antibody Rabbit Polyclonal ELISA 50440-RP01
    Anti-ICAM-1 Antibody Rabbit Monoclonal ELISA(Det) 50440-R101
    Anti-ICAM-1 Antibody Rabbit Monoclonal ELISA,ELISA(Cap),IHC-P 50440-R020
    Anti-ICAM-1 Antibody Rabbit Monoclonal IHC-P 50440-R280
    Anti-ICAM-1 Antibody Rabbit Monoclonal FCM 50440-R009
    Anti-ICAM-1 Antibody (PE) Rabbit Monoclonal FCM 50440-R009-P
    Anti-ICAM-1 Antibody (FITC) Rabbit Monoclonal FCM 50440-R009-F
    Anti-ICAM-1 Antibody Rabbit Monoclonal ELISA 10346-R013
    Anti-ICAM-1 Antibody (PE) Mouse Monoclonal FCM 10346-MM01-P
    Anti-ICAM-1 Antibody (PerCP) Mouse Monoclonal FCM 10346-MM01-C
    Anti-ICAM-1 Antibody (FITC) Mouse Monoclonal FCM 10346-MM01-F
    Anti-ICAM-1 Antibody Mouse Monoclonal ELISA,ELISA(Cap),FCM,ICC/IF,IF 10346-MM01
    Anti-ICAM-1 Antibody Mouse Monoclonal ELISA 10346-MM04
    Anti-ICAM-1 Antibody (APC) Mouse Monoclonal FCM 10346-MM01-A
    Anti-ICAM-1 Antibody Rabbit Polyclonal ELISA,IHC-P,ICC/IF,IF 10346-T26
    Anti-ICAM-1 Antibody Rabbit Polyclonal WB,ELISA,IHC-P,IP 10346-RP02
    Anti-ICAM-1 Antibody Rabbit Polyclonal ELISA 10346-T16
    Anti-ICAM-1 Antibody Rabbit Polyclonal ELISA 10346-RP01
    info info
    添加购物车成功! 添加购物车失败!