Huntington's Disease Therapeutic Targets

Protein Name	Alternative Names	BioChemical Class / Role	Products (Cat NO)
			Protein	Antibody	Gene cDNA clones
ABAT	FLJ17813, GABA-AT, GABAT, NPD009				HG10953-M, MG50224-M
P53	TP53, p53, LFS1, TRP53, FLJ92943				HG10182-M
TGM2/Transglutaminase 2	RP5-1054A22.2, G-ALPHA-h, GNAH, TG2, TGC	TGM2 is a member of the transglutaminase superfamily. Human TGM2 is implicated in the pathogenesis of several neurodegenerative disorders including Alzheimer's, Parkinson's and expanded polyglutamine (polyQ) diseases. It is also useful as a predictive marker for patient prognosis and may be a novel therapeutic target for colorectal cancer (CRC).	11095-H07B		HG11095-M
AKT1	AKT, PKB, RAC, PRKBA, MGC99656, PKB-ALPHA, RAC-ALPHA				HG10763-M, HG10763-M
CAPN5	FLJ46245, HTRA3, nCL-3				HG11390-M
Caspase-3	CASP3, CPP32, SCA-1, CPP32B				HG10050-M
Caspase-8/ALPS2B	CASP8, ALPS2B, CAP4, Casp-8, FLICE, FLJ17672, MACH, MCH5, MGC78473				HG10078-M
Caspase-9	CASP9, RP11-265F14.3, APAF-3, APAF3, CASPASE-9c, ICE-LAP6, MCH6				HG11151-M
GPX3	GPx-P, GSHPx-3, GSHPx-P				HG10940-M, MG50244-M
Kynureninase	KYNU, l-kynurenine hydrolase				HG10841-M, MG50310-M