OX40 qPCR Primer Pairs, Human

Cat: HP100503
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OX40 qPCR Primer Pairs, Human General Information
Target Details
Species:
Human
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
OX40 qPCR Primer Pairs, Human Alternative Names
ACT35 qPCR Primer Pairs, Human;CD134 qPCR Primer Pairs, Human;IMD16 qPCR Primer Pairs, Human;OX40 qPCR Primer Pairs, Human;TXGP1L qPCR Primer Pairs, Human
OX40 Background Information

OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a reactivation of antitumor immunity. The interaction between OX40 and OX40L plays an important role in antigen-specific T-cell expansion and survival. OX40 and OX40L also regulate cytokine production from T cells, antigen-presenting cells, natural killer cells, and natural killer T cells, and modulate cytokine receptor signaling. In line with these important modulatory functions, OX40-OX40L interactions have been found to play a central role in the development of multiple inflammatory and autoimmune diseases, making them attractive candidates for intervention in the clinic. Conversely, stimulating OX40 has shown it to be a candidate for therapeutic immunization strategies for cancer and infectious disease.

Immune Checkpoint
Immune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: WB Antibodies
Immune Checkpoint Proteins
Immune Checkpoint Targets   Co-stimulatory Immune Checkpoint Targets

Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
tumor necrosis factor receptor superfamily, member 4
References
  • Compaan D.M., et al. (2006) .The crystal structure of the costimulatory OX40-OX40L complex. Structure 14:1321-1330.
  • Kawamata S., et al. (1998) .Activation of OX40 signal transduction pathways leads to tumor necrosis factor receptor-associated factor (TRAF) 2- and TRAF5-mediated NF-kappaB activation. J. Biol. Chem. 273:5808-5814.
  • Byun M., (2013) Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood. J. Exp. Med. 210:1743-1759.
  • OX40 qPCR Primer Pairs, Cynomolgus, Related Products

    Product Name Catalog#(PDF)
    OX40 cDNA ORF Clone in Cloning Vector, Cynomolgus CG90873-G
    OX40 cDNA ORF Clone in Cloning Vector, Cynomolgus CG90846-G
    OX40 cDNA ORF Clone, Cynomolgus, untagged CG90846-UT
    OX40 Lentiviral cDNA ORF Clone, Cynomolgus, C-GFPSpark® tag CG90846-ACGLN
    OX40 cDNA ORF Clone, Cynomolgus, C-GFPSpark® tag CG90846-ACG
    OX40 cDNA ORF Clone, Cynomolgus, C-OFPSpark® tag CG90846-ACR
    OX40 cDNA ORF Clone, Cynomolgus, C-DDK (Flag®) tag CG90846-CF
    OX40 cDNA ORF Clone, Cynomolgus, N-DDK (Flag®) tag CG90846-NF
    OX40 cDNA ORF Clone, Cynomolgus, C-His tag CG90846-CH
    OX40 cDNA ORF Clone, Cynomolgus, N-His tag CG90846-NH
    OX40 cDNA ORF Clone, Cynomolgus, C-HA tag CG90846-CY
    OX40 cDNA ORF Clone, Cynomolgus, N-HA tag CG90846-NY
    OX40 cDNA ORF Clone, Cynomolgus, C-Myc tag CG90846-CM
    OX40 cDNA ORF Clone, Cynomolgus, N-Myc tag CG90846-NM

    OX40 qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
    OX40 cDNA ORF Clone, Rat, untagged RG84472-UT
    OX40 Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG84472-ACGLN
    OX40 cDNA ORF Clone, Rat, C-GFPSpark® tag RG84472-ACG
    OX40 cDNA ORF Clone, Rat, C-OFPSpark® tag RG84472-ACR
    OX40 cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG84472-CF
    OX40 cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG84472-NF
    OX40 cDNA ORF Clone, Rat, C-His tag RG84472-CH
    OX40 cDNA ORF Clone, Rat, N-His tag RG84472-NH
    OX40 cDNA ORF Clone, Rat, C-HA tag RG84472-CY
    OX40 cDNA ORF Clone, Rat, N-HA tag RG84472-NY
    OX40 cDNA ORF Clone, Rat, C-Myc tag RG84472-CM
    OX40 cDNA ORF Clone, Rat, N-Myc tag RG84472-NM

    OX40 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    OX40 cDNA ORF Clone in Cloning Vector, Mouse MG50808-G
    OX40 cDNA ORF Clone, Mouse, untagged MG50808-UT
    OX40 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50808-ACG
    OX40 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50808-ACGLN
    OX40 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50808-ACR
    OX40 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50808-CF
    OX40 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50808-NF
    OX40 cDNA ORF Clone, Mouse, C-His tag MG50808-CH
    OX40 cDNA ORF Clone, Mouse, N-His tag MG50808-NH
    OX40 cDNA ORF Clone, Mouse, C-HA tag MG50808-CY
    OX40 cDNA ORF Clone, Mouse, N-HA tag MG50808-NY
    OX40 cDNA ORF Clone, Mouse, C-Myc tag MG50808-CM
    OX40 cDNA ORF Clone, Mouse, N-Myc tag MG50808-NM

    OX40 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    OX40 cDNA ORF Clone in Cloning Vector, Human HG10481-G
    OX40 cDNA ORF Clone, Human, untagged HG10481-UT
    OX40 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10481-ACGLN
    OX40 cDNA ORF Clone, Human, C-GFPSpark® tag HG10481-ACG
    OX40 cDNA ORF Clone, Human, C-OFPSpark® tag HG10481-ACR
    OX40 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10481-CF
    OX40 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10481-NF
    OX40 cDNA ORF Clone, Human, C-His tag HG10481-CH
    OX40 cDNA ORF Clone, Human, N-His tag HG10481-NH
    OX40 cDNA ORF Clone, Human, C-HA tag HG10481-CY
    OX40 cDNA ORF Clone, Human, N-HA tag HG10481-NY
    OX40 cDNA ORF Clone, Human, C-Myc tag HG10481-CM
    OX40 cDNA ORF Clone, Human, N-Myc tag HG10481-NM
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