TIE2 cDNA ORF Clone, Human, C-Myc tag

Cat: HG10700-CM
Contact us:
+86-400-890-9989
order@sinobiological.com
Distributors
All TIE2 Reagents
CRO Services
Product recommended

All TIE2 Reagents
TIE2 cDNA ORF Clone, Human, C-Myc tag General Information
Gene
Species
Human
NCBI Ref Seq
RefSeq ORF Size
3375 bp
Description
Full length Clone DNA of Human TEK tyrosine kinase, endothelial with C terminal Myc tag.
Plasmid
Promoter
Enhanced CMV promoter
Vector
pCMV3-C-Myc
Tag Sequence
Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG
Sequencing Primers
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Kanamycin
Antibiotic in Mammalian cell
Hygromycin
Application
Stable or Transient mammalian expression
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

TIE2 cDNA ORF Clone, Human, C-Myc tag Alternative Names
CD202B cDNA ORF Clone, Human;TIE-2 cDNA ORF Clone, Human;TIE2 cDNA ORF Clone, Human;VMCM cDNA ORF Clone, Human;VMCM1 cDNA ORF Clone, Human
TIE2 Background Information

TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play critical roles in vascular maturation, maintenance of integrity and remodeling. Targeted mutagenesis of both Tek and its agonistic ligand, Angiopoietin-1, result in embryonic lethality, demonstrating that the signal transduction pathways mediated by this receptor are crucial for normal embryonic development. TEK signaling is indispensable for the development of the embryonic vasculature and suggests that TEK signaling may also be required for the development of the tumor vasculature.

Full Name
TEK tyrosine kinase, endothelial
References
  • Jones N, et al. (1998) The Tek / Tie2 receptor signals through a novel Dok-related docking protein, Dok-R. Oncogene. 17(9): 1097-108.
  • Sato A, et al. (1998) Characterization of TEK receptor tyrosine kinase and its ligands, Angiopoietins, in human hematopoietic progenitor cells. Int Immunol. 10(8): 1217-27.
  • Huang L, et al. (1995) GRB2 and SH-PTP2: potentially important endothelial signaling molecules downstream of the TEK / TIE2 receptor tyrosine kinase. Oncogene. 11(10): 2097-103.
  • TIE2 cDNA ORF Clone, Rat, Related Products

    Product Name Catalog#(PDF)
    TIE2 cDNA ORF Clone in Cloning Vector, Rat RG80063-M
    TIE2 cDNA ORF Clone, Rat, untagged RG80063-UT
    TIE2 cDNA ORF Clone, Rat, C-GFPSpark® tag RG80063-ACG
    TIE2 Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG80063-ACGLN
    TIE2 cDNA ORF Clone, Rat, C-OFPSpark® tag RG80063-ACR
    TIE2 cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80063-CF
    TIE2 cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80063-NF
    TIE2 cDNA ORF Clone, Rat, C-His tag RG80063-CH
    TIE2 cDNA ORF Clone, Rat, N-His tag RG80063-NH
    TIE2 cDNA ORF Clone, Rat, C-HA tag RG80063-CY
    TIE2 cDNA ORF Clone, Rat, N-HA tag RG80063-NY
    TIE2 cDNA ORF Clone, Rat, C-Myc tag RG80063-CM
    TIE2 cDNA ORF Clone, Rat, N-Myc tag RG80063-NM
    TIE2 qPCR Primer Pairs, Rat RP300061

    TIE2 cDNA ORF Clone, Mouse, Related Products

    Product Name Catalog#(PDF)
    TIE2 cDNA ORF Clone in Cloning Vector, Mouse MG51087-G
    TIE2 cDNA ORF Clone, Mouse, untagged MG51087-UT
    TIE2 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51087-ACG
    TIE2 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51087-ACGLN
    TIE2 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG51087-ACR
    TIE2 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG51087-CF
    TIE2 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG51087-NF
    TIE2 cDNA ORF Clone, Mouse, C-His tag MG51087-CH
    TIE2 cDNA ORF Clone, Mouse, N-His tag MG51087-NH
    TIE2 cDNA ORF Clone, Mouse, C-HA tag MG51087-CY
    TIE2 cDNA ORF Clone, Mouse, N-HA tag MG51087-NY
    TIE2 cDNA ORF Clone, Mouse, C-Myc tag MG51087-CM
    TIE2 cDNA ORF Clone, Mouse, N-Myc tag MG51087-NM
    TIE2 qPCR Primer Pairs, Mouse MP201045

    TIE2 cDNA ORF Clone, Human, Related Products

    Product Name Catalog#(PDF)
    TIE2 cDNA ORF Clone in Cloning Vector, Human HG10700-M
    TIE2 cDNA ORF Clone, Human, untagged HG10700-UT
    TIE2 cDNA ORF Clone, Human, C-GFPSpark® tag HG10700-ACG
    TIE2 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10700-ACGLN
    TIE2 cDNA ORF Clone, Human, C-OFPSpark® tag HG10700-ACR
    TIE2 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10700-CF
    TIE2 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10700-NF
    TIE2 cDNA ORF Clone, Human, C-His tag HG10700-CH
    TIE2 cDNA ORF Clone, Human, N-His tag HG10700-NH
    TIE2 cDNA ORF Clone, Human, C-HA tag HG10700-CY
    TIE2 cDNA ORF Clone, Human, N-HA tag HG10700-NY
    TIE2 cDNA ORF Clone, Human, N-Myc tag HG10700-NM
    TIE2 qPCR Primer Pairs, Human HP100881
    info info
    添加购物车成功! 添加购物车失败!