STIM1 qPCR Primer Pairs, Human

Cat: HP101311
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All STIM1 Reagents
CRO Services
Product recommended

All STIM1 Reagents
STIM1 qPCR Primer Pairs, Human General Information
Target Details
Species:
Human
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
STIM1 qPCR Primer Pairs, Human Alternative Names
D11S4896E qPCR Primer Pairs, Human;GOK qPCR Primer Pairs, Human;IMD10 qPCR Primer Pairs, Human;STRMK qPCR Primer Pairs, Human;TAM qPCR Primer Pairs, Human;TAM1 qPCR Primer Pairs, Human
STIM1 Background Information

Stromal interaction molecule 1, also known as STIM1 and GOK, is a cell membrane, a single-pass type I  membrane protein and a endoplasmic reticulum membrane protein. STIM1 / GOK is ubiquitously expressed in various human primary cells and tumor cell lines. It contains one EF-hand domain and one SAM (sterile alpha motif) domain. STIM1 / GOK plays a role in mediating Ca2+ influx following depletion of intracellular Ca2+ stores. It acts as Ca2+ sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca2+ depletion, STIM1 / GOK translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca2+ release-activated Ca2+ (CRAC) channel subunit, TMEM142A / ORAI1. Transfection of STIM1 / GOK into cells derived from a rhabdoid tumor and from a rhabdomyosarcoma that do not express detectable levels of STIM1 can induce cell death, suggesting a possible role in the control of rhabdomyosarcomas and rhabdoid tumors. Defects in STIM1 are the cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 2 (IDTICED2) which is an immune disorder characterized by recurrent infections, impaired T-cell activation and proliferative response, decreased T-cell production of cytokines, lymphadenopathy, and normal lymphocytes counts and serum immunoglobulin levels.

Full Name
stromal interaction molecule 1
References
  • Sabbioni S. et al., 1997, Cancer Res. 57: 4493-7.
  • Manji S.S. et al., 2000, Biochim. Biophys. Acta 1481: 147-55.
  • Williams R.T. et al., 2002, Biochim. Biophys. Acta. 1596: 131-7.
  • Spassova M.A. et al., 2006, Proc. Natl. Acad. Sci. USA. 103: 4040-5.
  • Parvez S. et al., 2008, FASEB J. 22: 752-61.
  • STIM1 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    STIM1 cDNA ORF Clone in Cloning Vector, Mouse MG50955-G
    STIM1 cDNA ORF Clone, Mouse, untagged MG50955-UT
    STIM1 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50955-ACGLN
    STIM1 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50955-ACG
    STIM1 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50955-ACR
    STIM1 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50955-CF
    STIM1 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50955-NF
    STIM1 cDNA ORF Clone, Mouse, C-His tag MG50955-CH
    STIM1 cDNA ORF Clone, Mouse, N-His tag MG50955-NH
    STIM1 cDNA ORF Clone, Mouse, C-HA tag MG50955-CY
    STIM1 cDNA ORF Clone, Mouse, N-HA tag MG50955-NY
    STIM1 cDNA ORF Clone, Mouse, C-Myc tag MG50955-CM
    STIM1 cDNA ORF Clone, Mouse, N-Myc tag MG50955-NM

    STIM1 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    STIM1 cDNA ORF Clone in Cloning Vector, Human HG11434-M
    STIM1 cDNA ORF Clone, Human, untagged HG11434-UT
    STIM1 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG11434-ACGLN
    STIM1 cDNA ORF Clone, Human, C-GFPSpark® tag HG11434-ACG
    STIM1 cDNA ORF Clone, Human, C-OFPSpark® tag HG11434-ACR
    STIM1 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG11434-CF
    STIM1 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG11434-NF
    STIM1 cDNA ORF Clone, Human, C-His tag HG11434-CH
    STIM1 cDNA ORF Clone, Human, N-His tag HG11434-NH
    STIM1 cDNA ORF Clone, Human, C-HA tag HG11434-CY
    STIM1 cDNA ORF Clone, Human, N-HA tag HG11434-NY
    STIM1 cDNA ORF Clone, Human, C-Myc tag HG11434-CM
    STIM1 cDNA ORF Clone, Human, N-Myc tag HG11434-NM
    info info
    添加购物车成功! 添加购物车失败!