STAT6 qPCR Primer Pairs, Human

Cat: HP102337
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STAT6 qPCR Primer Pairs, Human General Information
Target Details
Species:
Human
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
STAT6 qPCR Primer Pairs, Human Alternative Names
D12S1644 qPCR Primer Pairs, Human;IL-4-STAT qPCR Primer Pairs, Human;STAT6B qPCR Primer Pairs, Human;STAT6C qPCR Primer Pairs, Human
STAT6 Background Information

Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators like p300 and the CREB-binding protein (CBP). NF-?B and tyrosine-phosphorylated Stat6 can directly bind each other in vitro and in vivo, which suggest that the direct interaction between Stat6 and NF-?B may provide a basis for synergistic activation of transcription by IL-4 and activators of NF-?B. 

Full Name
signal transducer and activator of transcription 6, interleukin-4 induced
References
  • Litterst CM, et al. (2001) Transcriptional activation by STAT6 requires the direct interaction with NCoA-1. J Biol Chem. 276 (49): 45713-21.
  • Stutz AM, et al. (1999) Functional synergism of STAT6 with either NF-kappa B or PU.1 to mediate IL-4-induced activation of IgE germline gene transcription. J Immunol. 163 (8): 4383-91.
  • Yang J, et al. (2002) Identification of p100 as a coactivator for STAT6 that bridges STAT6 with RNA polymerase II. EMBO J. 21 (18): 4950-8.
  • STAT6 qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
    STAT6 cDNA ORF Clone in Cloning Vector, Rat RG81196-U
    STAT6 cDNA ORF Clone, Rat, untagged RG81196-UT
    STAT6 Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG81196-ACGLN
    STAT6 cDNA ORF Clone, Rat, C-GFPSpark® tag RG81196-ACG
    STAT6 cDNA ORF Clone, Rat, N-GFPSpark® tag RG81196-ANG
    STAT6 cDNA ORF Clone, Rat, C-OFPSpark® tag RG81196-ACR
    STAT6 cDNA ORF Clone, Rat, N-OFPSpark® tag RG81196-ANR
    STAT6 cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG81196-CF
    STAT6 cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG81196-NF
    STAT6 cDNA ORF Clone, Rat, C-His tag RG81196-CH
    STAT6 cDNA ORF Clone, Rat, N-His tag RG81196-NH
    STAT6 cDNA ORF Clone, Rat, C-HA tag RG81196-CY
    STAT6 cDNA ORF Clone, Rat, N-HA tag RG81196-NY
    STAT6 cDNA ORF Clone, Rat, C-Myc tag RG81196-CM
    STAT6 cDNA ORF Clone, Rat, N-Myc tag RG81196-NM

    STAT6 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    STAT6 cDNA ORF Clone in Cloning Vector, Mouse MG52975-U
    STAT6 cDNA ORF Clone, Mouse, untagged MG52975-UT
    STAT6 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG52975-ACG
    STAT6 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG52975-ACGLN
    STAT6 cDNA ORF Clone, Mouse, N-GFPSpark® tag MG52975-ANG
    STAT6 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG52975-ACR
    STAT6 cDNA ORF Clone, Mouse, N-OFPSpark® tag MG52975-ANR
    STAT6 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG52975-CF
    STAT6 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG52975-NF
    STAT6 cDNA ORF Clone, Mouse, C-His tag MG52975-CH
    STAT6 cDNA ORF Clone, Mouse, N-His tag MG52975-NH
    STAT6 cDNA ORF Clone, Mouse, C-HA tag MG52975-CY
    STAT6 cDNA ORF Clone, Mouse, N-HA tag MG52975-NY
    STAT6 cDNA ORF Clone, Mouse, C-Myc tag MG52975-CM
    STAT6 cDNA ORF Clone, Mouse, N-Myc tag MG52975-NM

    STAT6 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    STAT6 cDNA ORF Clone in Cloning Vector, Human HG13190-G
    STAT6 cDNA ORF Clone, Human, untagged HG13190-UT
    STAT6 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG13190-ACGLN
    STAT6 cDNA ORF Clone, Human, C-GFPSpark® tag HG13190-ACG
    STAT6 cDNA ORF Clone, Human, N-GFPSpark® tag HG13190-ANG
    STAT6 cDNA ORF Clone, Human, C-OFPSpark® tag HG13190-ACR
    STAT6 cDNA ORF Clone, Human, N-OFPSpark® tag HG13190-ANR
    STAT6 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG13190-CF
    STAT6 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG13190-NF
    STAT6 cDNA ORF Clone, Human, C-His tag HG13190-CH
    STAT6 cDNA ORF Clone, Human, N-His tag HG13190-NH
    STAT6 cDNA ORF Clone, Human, C-HA tag HG13190-CY
    STAT6 cDNA ORF Clone, Human, N-HA tag HG13190-NY
    STAT6 cDNA ORF Clone, Human, C-Myc tag HG13190-CM
    STAT6 cDNA ORF Clone, Human, N-Myc tag HG13190-NM
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