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Human PTPN2/TC-PTP transcript variant 2 Gene ORF cDNA clone expression plasmid, C-His tag

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Human PTPN2 cDNA Clone Product Information
NCBI RefSeq:NM_080422.1
RefSeq ORF Size:1164bp
cDNA Description:Full length Clone DNA of Homo sapiens protein tyrosine phosphatase, non-receptor type 2, transcript variant 2 with C terminal His tag.
Gene Synonym:PTPT, TCPTP, TC-PTP, TCELLPTP
Species:Human
Vector:pCMV3-C-His
Plasmid:
Restriction Site:
Tag Sequence:His Tag Sequence: CACCATCACCACCATCATCACCACCATCAC
Sequence Description:
Sequencing primers:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
Promoter:Enhanced CMV mammalian cell promoter
Application:Stable or Transient mammalian expression
Antibiotic in E.coli:Kanamycin
Antibiotic in mammalian cell:Hygromycin
Shipping_carrier:Each tube contains lyophilized plasmid.
Storage:The lyophilized plasmid can be stored at room temperature for three months.
His Tag Info

A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.

Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokarfyotic expression systems.

Human PTPN2/TC-PTP transcript variant 2 Gene ORF cDNA clone expression plasmid, C-His tag on other vectors
Human PTPN2/TC-PTP transcript variant 2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tagHG10571-ACG$225
Human PTPN2/TC-PTP transcript variant 2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tagHG10571-ACR$225
Human PTPN2/TC-PTP transcript variant 2 Gene ORF cDNA clone expression plasmid, N-GFPSpark tagHG10571-ANG$225
Human PTPN2/TC-PTP transcript variant 2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tagHG10571-ANR$225
Human PTPN2/TC-PTP transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Flag tagHG10571-CF$195
Human PTPN2/TC-PTP transcript variant 2 Gene ORF cDNA clone expression plasmid, C-His tagHG10571-CH$195
Human PTPN2/TC-PTP transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Myc tagHG10571-CM$195
Human PTPN2/TC-PTP transcript variant 2 Gene ORF cDNA clone expression plasmid, C-HA tagHG10571-CY$195
Human PTPN2/TC-PTP transcript variant 2 Gene ORF cDNA clone in cloning vectorHG10571-M$75
Human PTPN2/TC-PTP transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Flag tagHG10571-M-F$195
Human PTPN2/TC-PTP transcript variant 2 Gene ORF cDNA clone expression plasmid, N-Flag tagHG10571-NF$195
Human PTPN2/TC-PTP transcript variant 2 Gene ORF cDNA clone expression plasmid, N-His tagHG10571-NH$195
Human PTPN2/TC-PTP transcript variant 2 Gene ORF cDNA clone expression plasmid, N-Myc tagHG10571-NM$195
Human PTPN2/TC-PTP transcript variant 2 Gene ORF cDNA clone expression plasmid, N-HA tagHG10571-NY$195
Human PTPN2/TC-PTP transcript variant 2 Gene ORF cDNA clone expression plasmidHG10571-UT$195
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Background

Tyrosine-protein phosphatase non-receptor type 2, also known as T-cell protein-tyrosine phosphatase, PTPN2 and PTPT, is a cytoplasm protein which belongs to the protein-tyrosine phosphatase family and Non-receptor class 1 subfamily. Members of the protein tyrosine phosphatase ( PTP ) family share a highly conserved catalytic motif, which is essential for the catalytic activity. TC-PTP / PTPN2 is a cytosolic tyrosine phosphatase that functions as a negative regulator of a variety of tyrosine kinases and other signaling proteins. The expression of TC-PTP / PTPN2 plays a role of tumor suppressor and may modulate response to treatment. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. TC-PTP / PTPN2 is an enzyme that is essential for the proper functioning of the immune system and that participates in the control of cell proliferation, and inflammation. TC-PTP / PTPN2 was identified as a negative regulator of NUP214-ABL1 kinase activity.

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Catalog: HG10571-CH
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