|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human LOX-1 ORF mammalian expression plasmid, C-GFPSpark tag||HG10585-ACG|
|Human LOX-1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10585-ACR|
|Human LOX-1 ORF mammalian expression plasmid, C-Flag tag||HG10585-CF|
|Human LOX-1 ORF mammalian expression plasmid, C-His tag||HG10585-CH|
|Human LOX-1 ORF mammalian expression plasmid, C-Myc tag||HG10585-CM|
|Human LOX-1 ORF mammalian expression plasmid, C-HA tag||HG10585-CY|
|Human LOX-1 natural ORF mammalian expression plasmid||HG10585-M-N|
|Human LOX-1 ORF mammalian expression plasmid, N-Flag tag||HG10585-NF|
|Human LOX-1 ORF mammalian expression plasmid, N-His tag||HG10585-NH|
|Human LOX-1 ORF mammalian expression plasmid, N-Myc tag||HG10585-NM|
|Human LOX-1 ORF mammalian expression plasmid, N-HA tag||HG10585-NY|
|Human LOX-1 natural ORF mammalian expression plasmid||HG10585-UT|
|Learn more about expression Vectors|
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-ligand receptor originally identified as the endothelial oxidized LDL receptor. OLR1 / LOX1 was isolated from an aortic endothelial cell, and recently it has been discovered in macrophages and vascular smooth muscle cells in artery vessels. The expression of LOX1 is inducted by inflammatory stimuli and oxidative stimuli. This protein binds, internalizes and degrades oxidized low-density lipoprotein. LOX1 may play an important role in the progression of vulnerable carotid plaque and might regulate vulnerable plaque formation in cooperation with MMPs and TIMP-2. In clinical, LOX1 is thought to be involved in the development of atherosclerotic lesions.