IL24 qPCR Primer Pairs, Human

Cat: HP101878
Contact us:
+86-400-890-9989
order@sinobiological.com
Distributors
All IL24 Reagents
CRO Services
Product recommended

All IL24 Reagents
IL24 qPCR Primer Pairs, Human General Information
Target Details
Species:
Human
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
IL24 qPCR Primer Pairs, Human Alternative Names
C49A qPCR Primer Pairs, Human;FISP qPCR Primer Pairs, Human;IL10B qPCR Primer Pairs, Human;MDA7 qPCR Primer Pairs, Human;MOB5 qPCR Primer Pairs, Human;ST16 qPCR Primer Pairs, Human
IL24 Background Information

Interleukin-24 (IL-24) also known as Melanoma differentiation-associated gene 7 protein (MDA-7) is a member of the IL10 family of cytokines. IL-24/MDA-7/IL24 can induce apoptosis selectively in various cancer cells. Overexpression of IL-24 leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Human IL-24/MDA-7/IL24 is secreted by activated peripheral blood mononuclear cells and is the ligand for two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2. Northern blot analysis revealed IL-24/MDA-7/IL24 expression in human tissues associated with the immune system such as spleen, thymus, peripheral blood leukocytes and normal melanocytes. IL-24/MDA-7/IL24 binding to either its endogenous receptors on human keratinocytes or to ectopically expressed receptors on baby hamster kidney cells leads to activation of the signal transducers and activators of transcription.

Full Name
interleukin 24
References
  • Wang M, et al.. (2002) Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2. J Biol Chem. 277(9): 7341-7.
  • Sauane M, et al.. (2003) MDA-7/IL-24: novel cancer growth suppressing and apoptosis inducing cytokine. Cytokine Growth Factor Rev. 14(1): 35-51.
  • Sarkar D, et al.. (2002) mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK. Proc Natl Acad Sci U S A. 99(15): 10054-9.
  • IL24 qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
    IL24 cDNA ORF Clone in Cloning Vector, Rat RG80464-G
    IL24 cDNA ORF Clone, Rat, untagged RG80464-UT
    IL24 cDNA ORF Clone, Rat, C-GFPSpark® tag RG80464-ACG
    IL24 Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG80464-ACGLN
    IL24 cDNA ORF Clone, Rat, C-OFPSpark® tag RG80464-ACR
    IL24 cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80464-CF
    IL24 cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80464-NF
    IL24 cDNA ORF Clone, Rat, C-His tag RG80464-CH
    IL24 cDNA ORF Clone, Rat, N-His tag RG80464-NH
    IL24 cDNA ORF Clone, Rat, C-HA tag RG80464-CY
    IL24 cDNA ORF Clone, Rat, N-HA tag RG80464-NY
    IL24 cDNA ORF Clone, Rat, C-Myc tag RG80464-CM
    IL24 cDNA ORF Clone, Rat, N-Myc tag RG80464-NM

    IL24 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    IL24 cDNA ORF Clone in Cloning Vector, Mouse MG51067-G
    IL24 cDNA ORF Clone, Mouse, untagged MG51067-UT
    IL24 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51067-ACG
    IL24 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51067-ACGLN
    IL24 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG51067-ACR
    IL24 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG51067-CF
    IL24 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG51067-NF
    IL24 cDNA ORF Clone, Mouse, C-His tag MG51067-CH
    IL24 cDNA ORF Clone, Mouse, N-His tag MG51067-NH
    IL24 cDNA ORF Clone, Mouse, C-HA tag MG51067-CY
    IL24 cDNA ORF Clone, Mouse, N-HA tag MG51067-NY
    IL24 cDNA ORF Clone, Mouse, C-Myc tag MG51067-CM
    IL24 cDNA ORF Clone, Mouse, N-Myc tag MG51067-NM

    IL24 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    IL24 cDNA ORF Clone in Cloning Vector, Human HG12265-G
    IL24 cDNA ORF Clone, Human, untagged HG12265-UT
    IL24 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG12265-ACGLN
    IL24 cDNA ORF Clone, Human, C-GFPSpark® tag HG12265-ACG
    IL24 cDNA ORF Clone, Human, C-OFPSpark® tag HG12265-ACR
    IL24 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG12265-CF
    IL24 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG12265-NF
    IL24 cDNA ORF Clone, Human, C-His tag HG12265-CH
    IL24 cDNA ORF Clone, Human, N-His tag HG12265-NH
    IL24 cDNA ORF Clone, Human, C-HA tag HG12265-CY
    IL24 cDNA ORF Clone, Human, N-HA tag HG12265-NY
    IL24 cDNA ORF Clone, Human, C-Myc tag HG12265-CM
    IL24 cDNA ORF Clone, Human, N-Myc tag HG12265-NM
    info info
    添加购物车成功! 添加购物车失败!