HSP60 qPCR Primer Pairs, Human

Cat: HP101207
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All HSP60 Reagents
CRO Services
Product recommended

All HSP60 Reagents
HSP60 qPCR Primer Pairs, Human General Information
Target Details
Species:
Human
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
HSP60 qPCR Primer Pairs, Human Alternative Names
CPN60 qPCR Primer Pairs, Human;GROEL qPCR Primer Pairs, Human;HLD4 qPCR Primer Pairs, Human;HSP-60 qPCR Primer Pairs, Human;HSP60 qPCR Primer Pairs, Human;HSP65 qPCR Primer Pairs, Human;HuCHA60 qPCR Primer Pairs, Human;SPG13 qPCR Primer Pairs, Human
HSP60 Background Information

HSPD1, also known as HSP60, is a member of the chaperonin family. HSPD1 may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. It may also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. HSPD1 gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.Defects in HSPD1 are a cause of spastic paraplegia autosomal dominant type 13 (SPG13). Spastic paraplegia is a degenerative spinal cord disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Defects in HSPD1 are the cause of leukodystrophy hypomyelinating type 4 (HLD4); also called mitochondrial HSP60 chaperonopathy or MitCHAP-60 disease. HLD4 is a severe autosomal recessive hypomyelinating leukodystrophy. HSPD1 is cinically characterized by infantile-onset rotary nystagmus, progressive spastic paraplegia, neurologic regression, motor impairment, profound mental retardation. Death usually occurrs within the first two decades of life.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
heat shock 60kDa protein 1 (chaperonin)
References
  • Hansen J J, et al. (2002) Hereditary spastic paraplegia SPG13 is associated with a mutation in the gene encoding the mitochondrial chaperonin Hsp60. Am J Hum Genet. 70: 1328-32.
  • Magen D, et al. (2008) Mitochondrial Hsp60 chaperonopathy causes an autosomal-recessive neurodegenerative disorder linked to brain hypomyelination and leukodystrophy. Am J Hum Genet. 83: 30-42.
  • Venner TJ, et al. (1990) Nucleotide sequences and novel structural features of human and Chinese hamster hsp60 (chaperonin) gene families. DNA Cell Biol. 9 (8): 545-52.
  • HSP60 qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
    HSP60 cDNA ORF Clone in Cloning Vector, Rat RG81014-U
    HSP60 cDNA ORF Clone, Rat, untagged RG81014-UT
    HSP60 cDNA ORF Clone, Rat, C-GFPSpark® tag RG81014-ACG
    HSP60 Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG81014-ACGLN
    HSP60 cDNA ORF Clone, Rat, N-GFPSpark® tag RG81014-ANG
    HSP60 cDNA ORF Clone, Rat, C-OFPSpark® tag RG81014-ACR
    HSP60 cDNA ORF Clone, Rat, N-OFPSpark® tag RG81014-ANR
    HSP60 cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG81014-CF
    HSP60 cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG81014-NF
    HSP60 cDNA ORF Clone, Rat, C-His tag RG81014-CH
    HSP60 cDNA ORF Clone, Rat, N-His tag RG81014-NH
    HSP60 cDNA ORF Clone, Rat, C-HA tag RG81014-CY
    HSP60 cDNA ORF Clone, Rat, N-HA tag RG81014-NY
    HSP60 cDNA ORF Clone, Rat, C-Myc tag RG81014-CM
    HSP60 cDNA ORF Clone, Rat, N-Myc tag RG81014-NM

    HSP60 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    HSP60 cDNA ORF Clone in Cloning Vector, Mouse MG50596-U
    HSP60 cDNA ORF Clone, Mouse, untagged MG50596-UT
    HSP60 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50596-ACGLN
    HSP60 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50596-ACG
    HSP60 cDNA ORF Clone, Mouse, N-GFPSpark® tag MG50596-ANG
    HSP60 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50596-ACR
    HSP60 cDNA ORF Clone, Mouse, N-OFPSpark® tag MG50596-ANR
    HSP60 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50596-CF
    HSP60 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50596-NF
    HSP60 cDNA ORF Clone, Mouse, C-His tag MG50596-CH
    HSP60 cDNA ORF Clone, Mouse, N-His tag MG50596-NH
    HSP60 cDNA ORF Clone, Mouse, C-HA tag MG50596-CY
    HSP60 cDNA ORF Clone, Mouse, N-HA tag MG50596-NY
    HSP60 cDNA ORF Clone, Mouse, C-Myc tag MG50596-CM
    HSP60 cDNA ORF Clone, Mouse, N-Myc tag MG50596-NM

    HSP60 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    HSP60 cDNA ORF Clone in Cloning Vector, Human HG11322-M
    HSP60 cDNA ORF Clone, Human, untagged HG11322-UT
    HSP60 cDNA ORF Clone, Human, C-GFPSpark® tag HG11322-ACG
    HSP60 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG11322-ACGLN
    HSP60 cDNA ORF Clone, Human, N-GFPSpark® tag HG11322-ANG
    HSP60 cDNA ORF Clone, Human, C-OFPSpark® tag HG11322-ACR
    HSP60 cDNA ORF Clone, Human, N-OFPSpark® tag HG11322-ANR
    HSP60 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG11322-CF
    HSP60 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG11322-NF
    HSP60 cDNA ORF Clone, Human, C-His tag HG11322-CH
    HSP60 cDNA ORF Clone, Human, N-His tag HG11322-NH
    HSP60 cDNA ORF Clone, Human, C-HA tag HG11322-CY
    HSP60 cDNA ORF Clone, Human, N-HA tag HG11322-NY
    HSP60 cDNA ORF Clone, Human, C-Myc tag HG11322-CM
    HSP60 cDNA ORF Clone, Human, N-Myc tag HG11322-NM
    info info
    添加购物车成功! 添加购物车失败!