GLO1 qPCR Primer Pairs, Human

Cat: HP101855
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All GLO1 Reagents
CRO Services
Product recommended

All GLO1 Reagents
GLO1 qPCR Primer Pairs, Human General Information
Target Details
Species:
Human
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
GLO1 qPCR Primer Pairs, Human Alternative Names
GLOD1 qPCR Primer Pairs, Human;GLYI qPCR Primer Pairs, Human;HEL-S-74 qPCR Primer Pairs, Human
GLO1 Background Information

Lactoylglutathione lyase, also known as Methylglyoxalase, Aldoketomutase, Glyoxalase I, Ketone-aldehyde mutase, S-D-lactoylglutathione methylglyoxal lyase and GLO1, is a member of the glyoxalase I family. GLO1 / Glyoxalase I is a ubiquitous cellular defense enzyme involved in the detoxification of methylglyoxal, a cytotoxic byproduct of glycolysis. Accumulative evidence suggests an important role of GLO1 expression in protection against methylglyoxal-dependent protein adduction and cellular damage associated with diabetes, cancer, and chronological aging. GLO1 / Glyoxalase I has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. GLO1 / Glyoxalase I catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. GLO1 / Glyoxalase I exists in three separable isoforms which originate from two alleles in the genome. These correspond to two homodimers and one heterodimer composed of two subunits showing different electrophoretic properties. GLO1 upregulation may play a functional role in glycolytic adaptations of cancer cells.

Full Name
glyoxalase I
References
  • Wu, YY. et al., 2008,Prog Neuropsychopharmacol Biol Psychiatry. 32 (7):1740-4.
  • Williams,R. et al., 2009, PLoS One  4 (3): e4649.
  • Antognelli,C. et al., 2009, BMC Cancer  9 :115.
  • Bair,W.B. et al., 2010, Melanoma Res  20 (2):85-96.
  • GLO1 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    GLO1 cDNA ORF Clone in Cloning Vector, Mouse MG50364-M
    GLO1 cDNA ORF Clone, Mouse, untagged MG50364-UT
    GLO1 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50364-ACG
    GLO1 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50364-ACGLN
    GLO1 cDNA ORF Clone, Mouse, N-GFPSpark® tag MG50364-ANG
    GLO1 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50364-ACR
    GLO1 cDNA ORF Clone, Mouse, N-OFPSpark® tag MG50364-ANR
    GLO1 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50364-CF
    GLO1 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50364-NF
    GLO1 cDNA ORF Clone, Mouse, C-His tag MG50364-CH
    GLO1 cDNA ORF Clone, Mouse, N-His tag MG50364-NH
    GLO1 cDNA ORF Clone, Mouse, C-HA tag MG50364-CY
    GLO1 cDNA ORF Clone, Mouse, N-HA tag MG50364-NY
    GLO1 cDNA ORF Clone, Mouse, C-Myc tag MG50364-CM
    GLO1 cDNA ORF Clone, Mouse, N-Myc tag MG50364-NM

    GLO1 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    GLO1 cDNA ORF Clone in Cloning Vector, Human HG12223-G
    GLO1 cDNA ORF Clone, Human, untagged HG12223-UT
    GLO1 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG12223-ACGLN
    GLO1 cDNA ORF Clone, Human, C-GFPSpark® tag HG12223-ACG
    GLO1 cDNA ORF Clone, Human, N-GFPSpark® tag HG12223-ANG
    GLO1 cDNA ORF Clone, Human, C-OFPSpark® tag HG12223-ACR
    GLO1 cDNA ORF Clone, Human, N-OFPSpark® tag HG12223-ANR
    GLO1 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG12223-CF
    GLO1 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG12223-NF
    GLO1 cDNA ORF Clone, Human, C-His tag HG12223-CH
    GLO1 cDNA ORF Clone, Human, N-His tag HG12223-NH
    GLO1 cDNA ORF Clone, Human, C-HA tag HG12223-CY
    GLO1 cDNA ORF Clone, Human, N-HA tag HG12223-NY
    GLO1 cDNA ORF Clone, Human, C-Myc tag HG12223-CM
    GLO1 cDNA ORF Clone, Human, N-Myc tag HG12223-NM
    info info
    添加购物车成功! 添加购物车失败!