FOLR1 qPCR Primer Pairs, Human

Cat: HP101185
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All FOLR1 Reagents
CRO Services
Product recommended

All FOLR1 Reagents
FOLR1 qPCR Primer Pairs, Human General Information
Target Details
Species:
Human
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
FOLR1 qPCR Primer Pairs, Human Alternative Names
FBP qPCR Primer Pairs, Human;Folate Binding Protein qPCR Primer Pairs, Human;FOLR qPCR Primer Pairs, Human
FOLR1 Background Information

The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.
Folate receptor α (FRα) is the most important subunit of Folate receptor and the alpha isoform has been shown to be selectively overexpressed in cancer types like breast and ovarian cancer compared to normal breast and ovarian epithelial cells. It was determined that Folate receptor α exhibits a limited expression on the apical surfaces of the epithelial cells of normal lung, breast, thyroid, parathyroid, and kidney tissues. For their uptake of folate, normal cells rely almost exclusively on the reduced folate carrier, whereas many carcinomas and myeloid leukemia cells overexpress a high-affinity FR on their surfaces, perhaps reflecting their increased need for folate to support rapid cell division

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
folate receptor 1 (adult)
Research Areas
References
  • Senol S, Ceyran AB, Aydin A, et al. Folate receptor α expression and significance in endometrioid endometrium carcinoma and endometrial hyperplasia. International Journal of Clinical and Experimental Pathology. 2015;8(5):5633-5641.
  • FOLR1 qPCR Primer Pairs, Canine, Related Products

    Product Name Catalog#(PDF)
    FOLR1 cDNA ORF Clone in Cloning Vector, Canine DG70115-G

    FOLR1 qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
    FOLR1 cDNA ORF Clone in Cloning Vector, Rat RG81073-G

    FOLR1 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    FOLR1 cDNA ORF Clone in Cloning Vector, Mouse MG50573-M
    FOLR1 cDNA ORF Clone, Mouse, untagged MG50573-UT
    FOLR1 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50573-ACG
    FOLR1 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50573-ACGLN
    FOLR1 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50573-ACR
    FOLR1 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50573-CF
    FOLR1 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50573-NF
    FOLR1 cDNA ORF Clone, Mouse, C-His tag MG50573-CH
    FOLR1 cDNA ORF Clone, Mouse, N-His tag MG50573-NH
    FOLR1 cDNA ORF Clone, Mouse, C-HA tag MG50573-CY
    FOLR1 cDNA ORF Clone, Mouse, N-HA tag MG50573-NY
    FOLR1 cDNA ORF Clone, Mouse, C-Myc tag MG50573-CM
    FOLR1 cDNA ORF Clone, Mouse, N-Myc tag MG50573-NM

    FOLR1 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    FOLR1 cDNA ORF Clone in Cloning Vector, Human HG11241-M
    FOLR1 cDNA ORF Clone, Human, untagged HG11241-UT
    FOLR1 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG11241-ACGLN
    FOLR1 cDNA ORF Clone, Human, C-GFPSpark® tag HG11241-ACG
    FOLR1 cDNA ORF Clone, Human, C-OFPSpark® tag HG11241-ACR
    FOLR1 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG11241-CF
    FOLR1 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG11241-NF
    FOLR1 cDNA ORF Clone, Human, C-His tag HG11241-CH
    FOLR1 cDNA ORF Clone, Human, N-His tag HG11241-NH
    FOLR1 cDNA ORF Clone, Human, C-HA tag HG11241-CY
    FOLR1 cDNA ORF Clone, Human, N-HA tag HG11241-NY
    FOLR1 cDNA ORF Clone, Human, C-Myc tag HG11241-CM
    FOLR1 cDNA ORF Clone, Human, N-Myc tag HG11241-NM
    info info
    添加购物车成功! 添加购物车失败!