FGFRL1 qPCR Primer Pairs, Human

Cat: HP102275
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FGFRL1 qPCR Primer Pairs, Human General Information
Target Details
Species:
Human
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
FGFRL1 qPCR Primer Pairs, Human Alternative Names
FGFR5 qPCR Primer Pairs, Human;FHFR qPCR Primer Pairs, Human
FGFRL1 Background Information

Fibroblast growth factor receptor-like 1 (FGFRL1) also known as Fibroblast growth factor receptor 5 (FGFR5), is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A unique feature of FGFRL1/FGFR5 is that it does not contain an intracellular tyrosine kinase domain. Some muscle types, including the muscles of the tongue and the diaphragm, express FGFRL1/FGFR5 at relatively high level. In contrast, the heart and the skeletal muscles of the limbs, as well as many other organs (brain, lung, liver, kidney, gut) express Fgfrl1 only at basal level. It is conceivable that FGFRL1/FGFR5 interacts with other Fgfrs, which are expressed in cartilage and muscle, to modulate FGF signaling.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
fibroblast growth factor receptor-like 1
References
  • Wiedemann M, et al. (2000) Characterization of a novel protein (FGFRL1) from human cartilage related to FGF receptors. Genomics. 69(2): 275-9.
  • Trueb B, et al. (2006) Expression of FGFRL1, a novel fibroblast growth factor receptor, during embryonic development. Int J Mol Med. 17(4): 617-20.
  • Wiedemann M, et al. (2001) The mouse Fgfrl1 gene coding for a novel FGF receptor-like protein. Biochim Biophys Acta. 1520(3): 247-50.
  • Trueb B, et al. (2003) Characterization of FGFRL1, a novel fibroblast growth factor (FGF) receptor preferentially expressed in skeletal tissues. J Biol Chem. 278(36): 33857-65.
  • FGFRL1 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    FGFRL1 cDNA ORF Clone in Cloning Vector, Mouse MG50182-M
    FGFRL1 cDNA ORF Clone, Mouse, untagged MG50182-UT
    FGFRL1 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50182-ACGLN
    FGFRL1 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50182-ACG
    FGFRL1 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50182-ACR
    FGFRL1 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50182-CF
    FGFRL1 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50182-NF
    FGFRL1 cDNA ORF Clone, Mouse, C-His tag MG50182-CH
    FGFRL1 cDNA ORF Clone, Mouse, N-His tag MG50182-NH
    FGFRL1 cDNA ORF Clone, Mouse, C-HA tag MG50182-CY
    FGFRL1 cDNA ORF Clone, Mouse, N-HA tag MG50182-NY
    FGFRL1 cDNA ORF Clone, Mouse, C-Myc tag MG50182-CM
    FGFRL1 cDNA ORF Clone, Mouse, N-Myc tag MG50182-NM

    FGFRL1 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    FGFRL1 cDNA ORF Clone in Cloning Vector, Human HG13589-G
    FGFRL1 cDNA ORF Clone, Human, untagged HG13589-UT
    FGFRL1 cDNA ORF Clone, Human, C-GFPSpark® tag HG13589-ACG
    FGFRL1 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG13589-ACGLN
    FGFRL1 cDNA ORF Clone, Human, C-OFPSpark® tag HG13589-ACR
    FGFRL1 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG13589-CF
    FGFRL1 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG13589-NF
    FGFRL1 cDNA ORF Clone, Human, C-His tag HG13589-CH
    FGFRL1 cDNA ORF Clone, Human, N-His tag HG13589-NH
    FGFRL1 cDNA ORF Clone, Human, C-HA tag HG13589-CY
    FGFRL1 cDNA ORF Clone, Human, N-HA tag HG13589-NY
    FGFRL1 cDNA ORF Clone, Human, C-Myc tag HG13589-CM
    FGFRL1 cDNA ORF Clone, Human, N-Myc tag HG13589-NM
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