FGF18 qPCR Primer Pairs, Human

Cat: HP101880
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FGF18 qPCR Primer Pairs, Human General Information
Target Details
Species:
Human
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
FGF18 qPCR Primer Pairs, Human Alternative Names
FGF-18 qPCR Primer Pairs, Human;ZFGF5 qPCR Primer Pairs, Human
FGF18 Background Information

Fibroblast growth factor 18 (FGF18) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that FGF18 is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Experiment datas identified FGF18 as a selective ligand for FGFR3 in limb bud mesenchymal cells, which suppressed proliferation and promoted their differentiation and production of cartilage matrix. FGF18 appears to regulate cell proliferation and differentiation positively in osteogenesis and negatively in chondrogenesis.

Full Name
fibroblast growth factor 18
References
  • Ohbayashi N, et al. (2002) FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev. 16(7): 870-9.
  • Davidson D, et al. (2005) Fibroblast growth factor (FGF) 18 signals through FGF receptor 3 to promote chondrogenesis. J Biol Chem. 280(21): 20509-15.
  • Liu Z, et al. (2007) FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate. Dev Biol. 302(1): 80-91.
  • FGF18 qPCR Primer Pairs, Canine, Related Products

    Product Name Catalog#(PDF)
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    FGF18 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
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    FGF18 cDNA ORF Clone, Mouse, C-HA tag MG50177-CY
    FGF18 cDNA ORF Clone, Mouse, N-HA tag MG50177-NY
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    FGF18 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    FGF18 cDNA ORF Clone in Cloning Vector, Human HG13206-G
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    FGF18 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG13206-ACGLN
    FGF18 cDNA ORF Clone, Human, C-OFPSpark® tag HG13206-ACR
    FGF18 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG13206-CF
    FGF18 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG13206-NF
    FGF18 cDNA ORF Clone, Human, C-His tag HG13206-CH
    FGF18 cDNA ORF Clone, Human, N-His tag HG13206-NH
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    FGF18 cDNA ORF Clone, Human, N-HA tag HG13206-NY
    FGF18 cDNA ORF Clone, Human, C-Myc tag HG13206-CM
    FGF18 cDNA ORF Clone, Human, N-Myc tag HG13206-NM
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