Factor XIII qPCR Primer Pairs, Human

Cat: HP101381
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Factor XIII qPCR Primer Pairs, Human General Information
Target Details
Species:
Human
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
Factor XIII qPCR Primer Pairs, Human Alternative Names
Coagulation factor 13 qPCR Primer Pairs, Human;Coagulation factor XIII qPCR Primer Pairs, Human;FXIIIB qPCR Primer Pairs, Human
Factor XIII Background Information

Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 10 Sushi ( CCP / SCR ) domains. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is composed of just 2 A subunits, which are identical to those of plasma origin. The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin. Factor XIII acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. Defects in F13B are the cause of factor XIII subunit B deficiency ( FA13BD ) which is an autosomal recessive disorder characterized by a life-long bleeding tendency, impaired wound healing and spontaneous abortion in affected women.

Full Name
coagulation factor XIII, B polypeptide
References
  • Bottenus R.E., et al.,(1990), Nucleotide sequence of the gene for the b subunit of human factor XIII. Biochemistry 29:11195-11209.
  • Ichinose A., et al., (1986), Amino acid sequence of the b subunit of human factor XIII, a protein composed of ten repetitive segments.Biochemistry 25:4633-4638.
  • Ota T., et al.,(2004), Complete sequencing and characterization of 21,243 full-length human cDNAs.Nat. Genet. 36:40-45.
  • Factor XIII qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    Factor XIII cDNA ORF Clone in Cloning Vector, Mouse MG5A3395-U
    Factor XIII cDNA ORF Clone, Mouse, untagged MG5A3395-UT
    Factor XIII Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG5A3395-ACGLN
    Factor XIII cDNA ORF Clone, Mouse, C-GFPSpark® tag MG5A3395-ACG
    Factor XIII cDNA ORF Clone, Mouse, C-OFPSpark® tag MG5A3395-ACR
    Factor XIII cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG5A3395-CF
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    Factor XIII cDNA ORF Clone, Mouse, C-His tag MG5A3395-CH
    Factor XIII cDNA ORF Clone, Mouse, N-His tag MG5A3395-NH
    Factor XIII cDNA ORF Clone, Mouse, C-HA tag MG5A3395-CY
    Factor XIII cDNA ORF Clone, Mouse, N-HA tag MG5A3395-NY
    Factor XIII cDNA ORF Clone, Mouse, C-Myc tag MG5A3395-CM
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    Factor XIII qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    Factor XIII cDNA ORF Clone in Cloning Vector, Human HG11510-M
    Factor XIII cDNA ORF Clone, Human, untagged HG11510-UT
    Factor XIII Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG11510-ACGLN
    Factor XIII cDNA ORF Clone, Human, C-GFPSpark® tag HG11510-ACG
    Factor XIII cDNA ORF Clone, Human, C-OFPSpark® tag HG11510-ACR
    Factor XIII cDNA ORF Clone, Human, C-DDK (Flag®) tag HG11510-CF
    Factor XIII cDNA ORF Clone, Human, N-DDK (Flag®) tag HG11510-NF
    Factor XIII cDNA ORF Clone, Human, C-His tag HG11510-CH
    Factor XIII cDNA ORF Clone, Human, N-His tag HG11510-NH
    Factor XIII cDNA ORF Clone, Human, C-HA tag HG11510-CY
    Factor XIII cDNA ORF Clone, Human, N-HA tag HG11510-NY
    Factor XIII cDNA ORF Clone, Human, C-Myc tag HG11510-CM
    Factor XIII cDNA ORF Clone, Human, N-Myc tag HG11510-NM
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