Cystatin C qPCR Primer Pairs, Human

Cat: HP100468
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Cystatin C qPCR Primer Pairs, Human General Information
Target Details
Species:
Human
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
Cystatin C qPCR Primer Pairs, Human Alternative Names
ARMD11 qPCR Primer Pairs, Human
Cystatin C Background Information

Cystatin C, also known as Cystatin-3 (CST3) is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal function, particularly to detect small reductions in glomerular filtration rate. The mature, active form of human cystatin C is a single non-glycosylated polypeptide chain consisting of 120 amino acid residues, with a molecular mass of 13,343-13,359 Da, and containing four characteristic disulfide-paired cysteine residues. Cystatin C is a low-molecular-weight protein which has been proposed as a marker of renal function that could replace creatinine. Indeed, the concentration of Cystatin C is mainly determined by glomerular filtration and is particularly of interest in clinical settings where the relationship between creatinine production and muscle mass impairs the clinical performance of creatinine. Since the last decade, numerous studies have evaluated its potential use in measuring renal function in various populations. More recently, other potential developments for its clinical use have emerged. In almost all the clinical studies, Cystatin C demonstrated a better diagnostic accuracy than serum creatinine in discriminating normal from impaired kidney function, but controversial results have been obtained by comparing this protein with other indices of kidney disease, especially serum creatinine-based equations, such as early atherosclerosis, Alzheimer's dementia, vascular aneurysms, hyperhomocysteinaemia and other neurodegenerative diseases. Cystatin C could be a useful clinical tool to identify HIV-infected persons. In addition, its expression is up-regulated in malignance of certain tumor progression.

Full Name
cystatin C
References
  • Mares J, et al. (2003) Use of cystatin C determination in clinical diagnostics. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 147(2): 177-80.
  • Mussap M, et al. (2004) Biochemistry and clinical role of human cystatin C. Crit Rev Clin Lab Sci. 41(5-6): 467-550.
  • Sronie-Vivien S, et al. (2008) Cystatin C: current position and future prospects. Clin Chem Lab Med. 46(12): 1664-86.
  • Taglieri N, et al. (2009) Cystatin C and cardiovascular risk. Clin Chem. 55(11): 1932-43.
  • Cystatin C qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
    Cystatin C cDNA ORF Clone in Cloning Vector, Rat RG80040-M
    Cystatin C cDNA ORF Clone, Rat, untagged RG80040-UT
    Cystatin C Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG80040-ACGLN
    Cystatin C cDNA ORF Clone, Rat, C-GFPSpark® tag RG80040-ACG
    Cystatin C cDNA ORF Clone, Rat, C-OFPSpark® tag RG80040-ACR
    Cystatin C cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80040-CF
    Cystatin C cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80040-NF
    Cystatin C cDNA ORF Clone, Rat, C-His tag RG80040-CH
    Cystatin C cDNA ORF Clone, Rat, N-His tag RG80040-NH
    Cystatin C cDNA ORF Clone, Rat, C-HA tag RG80040-CY
    Cystatin C cDNA ORF Clone, Rat, N-HA tag RG80040-NY
    Cystatin C cDNA ORF Clone, Rat, C-Myc tag RG80040-CM
    Cystatin C cDNA ORF Clone, Rat, N-Myc tag RG80040-NM

    Cystatin C qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    Cystatin C cDNA ORF Clone in Cloning Vector, Mouse MG50239-M
    Cystatin C cDNA ORF Clone, Mouse, untagged MG50239-UT
    Cystatin C Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50239-ACGLN
    Cystatin C cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50239-ACG
    Cystatin C cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50239-ACR
    Cystatin C cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50239-CF
    Cystatin C cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50239-NF
    Cystatin C cDNA ORF Clone, Mouse, C-His tag MG50239-CH
    Cystatin C cDNA ORF Clone, Mouse, N-His tag MG50239-NH
    Cystatin C cDNA ORF Clone, Mouse, C-HA tag MG50239-CY
    Cystatin C cDNA ORF Clone, Mouse, N-HA tag MG50239-NY
    Cystatin C cDNA ORF Clone, Mouse, C-Myc tag MG50239-CM
    Cystatin C cDNA ORF Clone, Mouse, N-Myc tag MG50239-NM

    Cystatin C qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    Cystatin C cDNA ORF Clone in Cloning Vector, Human HG10439-G
    Cystatin C cDNA ORF Clone, Human, untagged HG10439-UT
    Cystatin C Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10439-ACGLN
    Cystatin C cDNA ORF Clone, Human, C-GFPSpark® tag HG10439-ACG
    Cystatin C cDNA ORF Clone, Human, C-OFPSpark® tag HG10439-ACR
    Cystatin C cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10439-CF
    Cystatin C cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10439-NF
    Cystatin C cDNA ORF Clone, Human, C-His tag HG10439-CH
    Cystatin C cDNA ORF Clone, Human, N-His tag HG10439-NH
    Cystatin C cDNA ORF Clone, Human, C-HA tag HG10439-CY
    Cystatin C cDNA ORF Clone, Human, N-HA tag HG10439-NY
    Cystatin C cDNA ORF Clone, Human, C-Myc tag HG10439-CM
    Cystatin C cDNA ORF Clone, Human, N-Myc tag HG10439-NM
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