CDH17 qPCR Primer Pairs, Human

Cat: HP101244
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CDH17 qPCR Primer Pairs, Human General Information
Target Details
Species:
Human
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
CDH17 qPCR Primer Pairs, Human Alternative Names
CDH16 qPCR Primer Pairs, Human;HPT-1 qPCR Primer Pairs, Human;HPT1 qPCR Primer Pairs, Human
CDH17 Background Information

Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular region, 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing of the encoding gene results in multiple transcript variants. Cadherin-17/LI-cadherin preferentially interact with themselves in a homophilic manner in connecting cells. Cadherin-17 may thus contribute to the sorting of heterogeneous cell types and have a role in the morphological organization of liver and intestine. It's also involved in intestinal peptide transport. Experiments have reported the association between Cadherin-17/LI-cadherin and gastric cancer. Cadherin-17/LI-cadherin expression was detected in 63/94 of gastric adenocarcinomas in addition to intestinal metaplasia. The expression of Cadherin-17 tended to be associated with intestinal type carcinoma, and carcinomas with Cadherin-17 expression was significantly more frequent in advanced stage cases than in early stage. Cadherin-17 is also a useful immunohistochemical marker for diagnosis of adenocarcinomas of the digestive system.

Full Name
cadherin 17, LI cadherin (liver-intestine)
References
  • Liu LX, et al. (2009) Targeting cadherin-17 inactivates Wnt signaling and inhibits tumor growth in liver carcinoma. Hepatology. 50(5): 1453-63.
  • Ito R, et al. (2005) Clinicopathological significant and prognostic influence of cadherin-17 expression in gastric cancer. Virchows Arch. 447(4): 717-22.
  • Horsfield J, et al. (2002) Cadherin-17 is required to maintain pronephric duct integrity during zebrafish development. Mech Dev. 115(1-2): 15-26.
  • CDH17 qPCR Primer Pairs, Rhesus, Related Products

    Product Name Catalog#(PDF)
    CDH17 cDNA ORF Clone in Cloning Vector, Rhesus CG90147-G
    CDH17 cDNA ORF Clone, Rhesus, untagged CG90147-UT
    CDH17 cDNA ORF Clone, Rhesus, C-GFPSpark® tag CG90147-ACG
    CDH17 Lentiviral cDNA ORF Clone, Rhesus, C-GFPSpark® tag CG90147-ACGLN
    CDH17 cDNA ORF Clone, Rhesus, C-OFPSpark® tag CG90147-ACR
    CDH17 cDNA ORF Clone, Rhesus, C-DDK (Flag®) tag CG90147-CF
    CDH17 cDNA ORF Clone, Rhesus, N-DDK (Flag®) tag CG90147-NF
    CDH17 cDNA ORF Clone, Rhesus, C-His tag CG90147-CH
    CDH17 cDNA ORF Clone, Rhesus, N-His tag CG90147-NH
    CDH17 cDNA ORF Clone, Rhesus, C-HA tag CG90147-CY
    CDH17 cDNA ORF Clone, Rhesus, N-HA tag CG90147-NY
    CDH17 cDNA ORF Clone, Rhesus, C-Myc tag CG90147-CM
    CDH17 cDNA ORF Clone, Rhesus, N-Myc tag CG90147-NM

    CDH17 qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
    CDH17 cDNA ORF Clone in Cloning Vector, Rat RG80283-G
    CDH17 cDNA ORF Clone, Rat, untagged RG80283-UT
    CDH17 cDNA ORF Clone, Rat, C-GFPSpark® tag RG80283-ACG
    CDH17 Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG80283-ACGLN
    CDH17 cDNA ORF Clone, Rat, C-OFPSpark® tag RG80283-ACR
    CDH17 cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80283-CF
    CDH17 cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80283-NF
    CDH17 cDNA ORF Clone, Rat, C-His tag RG80283-CH
    CDH17 cDNA ORF Clone, Rat, N-His tag RG80283-NH
    CDH17 cDNA ORF Clone, Rat, C-HA tag RG80283-CY
    CDH17 cDNA ORF Clone, Rat, N-HA tag RG80283-NY
    CDH17 cDNA ORF Clone, Rat, C-Myc tag RG80283-CM
    CDH17 cDNA ORF Clone, Rat, N-Myc tag RG80283-NM

    CDH17 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    CDH17 cDNA ORF Clone in Cloning Vector, Mouse MG50942-G
    CDH17 cDNA ORF Clone, Mouse, untagged MG50942-UT
    CDH17 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50942-ACGLN
    CDH17 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50942-ACG
    CDH17 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50942-ACR
    CDH17 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50942-CF
    CDH17 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50942-NF
    CDH17 cDNA ORF Clone, Mouse, C-His tag MG50942-CH
    CDH17 cDNA ORF Clone, Mouse, N-His tag MG50942-NH
    CDH17 cDNA ORF Clone, Mouse, C-HA tag MG50942-CY
    CDH17 cDNA ORF Clone, Mouse, N-HA tag MG50942-NY
    CDH17 cDNA ORF Clone, Mouse, C-Myc tag MG50942-CM
    CDH17 cDNA ORF Clone, Mouse, N-Myc tag MG50942-NM

    CDH17 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    CDH17 cDNA ORF Clone in Cloning Vector, Human HG11360-M
    CDH17 cDNA ORF Clone, Human, untagged HG11360-UT
    CDH17 cDNA ORF Clone, Human, C-GFPSpark® tag HG11360-ACG
    CDH17 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG11360-ACGLN
    CDH17 cDNA ORF Clone, Human, C-OFPSpark® tag HG11360-ACR
    CDH17 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG11360-CF
    CDH17 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG11360-NF
    CDH17 cDNA ORF Clone, Human, C-His tag HG11360-CH
    CDH17 cDNA ORF Clone, Human, N-His tag HG11360-NH
    CDH17 cDNA ORF Clone, Human, C-HA tag HG11360-CY
    CDH17 cDNA ORF Clone, Human, N-HA tag HG11360-NY
    CDH17 cDNA ORF Clone, Human, C-Myc tag HG11360-CM
    CDH17 cDNA ORF Clone, Human, N-Myc tag HG11360-NM
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