CD46 qPCR Primer Pairs, Human

Cat: HP100030
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CD46 qPCR Primer Pairs, Human General Information
Target Details
Species:
Human
PCR Size:
98bp
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
CD46 qPCR Primer Pairs, Human Validated Images
Human CD46 qPCR 5501
CD46 amplification curves
Human CD46 qPCR 5500
CD46 dissolution curves
CD46 qPCR Primer Pairs, Human Alternative Names
AHUS2 qPCR Primer Pairs, Human;MCP qPCR Primer Pairs, Human;MIC10 qPCR Primer Pairs, Human;TLX qPCR Primer Pairs, Human;TRA2.10 qPCR Primer Pairs, Human
CD46 Background Information

CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white blood cells, platelets, epithelial cells, and fibroblasts. Human CD46 shares 50% amino acid sequence identity with mouse and rat CD46. The importance of CD46 to complement regulation is underscored by the observation that genetic loss of CD46 leads to development of atypical hemolytic-uremic syndrome (aHUS), a disease characterized by uncontrolled complement activation. CD46 is implicated in the development and/or progression of selected cancer types.

Full Name
CD46 molecule, complement regulatory protein
References
  • Lublin D.M., et al.,(1988), Molecular cloning and chromosomal localization of human membrane cofactor protein (MCP). Evidence for inclusion in the multigene family of complement-regulatory proteins. J. Exp. Med. 168:181-194.
  • Purcell D.F., et al., (1991), Alternatively spliced RNAs encode several isoforms of CD46 (MCP), a regulator of complement activation.Immunogenetics 33:335-344.
  • Post T.W., et al.,(1991), Membrane cofactor protein of the complement system: alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms that correlate with protein phenotype.J. Exp. Med. 174:93-102.
  • CD46 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    CD46 cDNA ORF Clone, Mouse, untagged MG59760-UT
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    CD46 cDNA ORF Clone, Mouse, C-His tag MG59760-CH
    CD46 cDNA ORF Clone, Mouse, N-His tag MG59760-NH
    CD46 cDNA ORF Clone, Mouse, C-HA tag MG59760-CY
    CD46 cDNA ORF Clone, Mouse, N-HA tag MG59760-NY
    CD46 cDNA ORF Clone, Mouse, C-Myc tag MG59760-CM
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    CD46 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    CD46 cDNA ORF Clone in Cloning Vector, Human HG12239-G
    CD46 cDNA ORF Clone, Human, untagged HG12239-UT
    CD46 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG12239-ACGLN
    CD46 cDNA ORF Clone, Human, C-GFPSpark® tag HG12239-ACG
    CD46 cDNA ORF Clone, Human, N-GFPSpark® tag HG12239-ANG
    CD46 cDNA ORF Clone, Human, C-OFPSpark® tag HG12239-ACR
    CD46 cDNA ORF Clone, Human, N-OFPSpark® tag HG12239-ANR
    CD46 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG12239-CF
    CD46 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG12239-NF
    CD46 cDNA ORF Clone, Human, C-His tag HG12239-CH
    CD46 cDNA ORF Clone, Human, N-His tag HG12239-NH
    CD46 cDNA ORF Clone, Human, C-HA tag HG12239-CY
    CD46 cDNA ORF Clone, Human, N-HA tag HG12239-NY
    CD46 cDNA ORF Clone, Human, C-Myc tag HG12239-CM
    CD46 cDNA ORF Clone, Human, N-Myc tag HG12239-NM
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