CCL20 qPCR Primer Pairs, Human

Cat: HP100507
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CCL20 qPCR Primer Pairs, Human General Information
Target Details
Species:
Human
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
CCL20 qPCR Primer Pairs, Human Alternative Names
CKb4 qPCR Primer Pairs, Human;Exodus qPCR Primer Pairs, Human;LARC qPCR Primer Pairs, Human;MIP-3-alpha qPCR Primer Pairs, Human;MIP-3a qPCR Primer Pairs, Human;MIP3A qPCR Primer Pairs, Human;SCYA20 qPCR Primer Pairs, Human;ST38 qPCR Primer Pairs, Human
CCL20 Background Information

Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family that attracts immature dendritic cells and memory T lymphocytes, both expressing CCR6. Depending on the cell type, this chemokine was found to be inducible by cytokines (IL-1beta) and by bacterial, viral, or plant products (including LPS, dsRNA, and PMA). MIP3A / CCL20 is Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of MIP3A / CCL20 has been seen in thymus, prostate, testis, small intestine and colon. As a chemotactic factor, MIP3A / CCL20 attracts lymphocytes and, slightly, neutrophils, but not monocytes. This chemokine may Inhibit proliferation of myeloid progenitors in colony formation assays and it may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. Its C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Chemokine CCL20 was shown to play a role in colorectal cancer (CRC) pathogenesis.

Full Name
chemokine (C-C motif) ligand 20
References
  • Vicinus B, et al. (2012) miR-21 functionally interacts with the 3'UTR of chemokine CCL20 and down-regulates CCL20 expression in miR-21 transfected colorectal cancer cells. Cancer Lett. 316(1): 105-12.
  • Ding X, et al. (2012) High Expression of CCL20 Is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma after Curative Resection. J Gastrointest Surg. 16(4): 828-36.
  • Ivison SM, et al. (2010) Oxidative stress enhances IL-8 and inhibits CCL20 production from intestinal epithelial cells in response to bacterial flagellin. Am J Physiol Gastrointest Liver Physiol. 299(3): 733-41.
  • CCL20 qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
    CCL20 cDNA ORF Clone in Cloning Vector, Rat RG80036-M
    CCL20 cDNA ORF Clone, Rat, untagged RG80036-UT
    CCL20 Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG80036-ACGLN
    CCL20 cDNA ORF Clone, Rat, C-GFPSpark® tag RG80036-ACG
    CCL20 cDNA ORF Clone, Rat, C-OFPSpark® tag RG80036-ACR
    CCL20 cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80036-CF
    CCL20 cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80036-NF
    CCL20 cDNA ORF Clone, Rat, C-His tag RG80036-CH
    CCL20 cDNA ORF Clone, Rat, N-His tag RG80036-NH
    CCL20 cDNA ORF Clone, Rat, C-HA tag RG80036-CY
    CCL20 cDNA ORF Clone, Rat, N-HA tag RG80036-NY
    CCL20 cDNA ORF Clone, Rat, C-Myc tag RG80036-CM
    CCL20 cDNA ORF Clone, Rat, N-Myc tag RG80036-NM

    CCL20 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    CCL20 cDNA ORF Clone in Cloning Vector, Mouse MG50048-M
    CCL20 cDNA ORF Clone, Mouse, untagged MG50048-UT
    CCL20 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50048-ACG
    CCL20 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50048-ACGLN
    CCL20 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50048-ACR
    CCL20 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50048-CF
    CCL20 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50048-NF
    CCL20 cDNA ORF Clone, Mouse, C-His tag MG50048-CH
    CCL20 cDNA ORF Clone, Mouse, N-His tag MG50048-NH
    CCL20 cDNA ORF Clone, Mouse, C-HA tag MG50048-CY
    CCL20 cDNA ORF Clone, Mouse, N-HA tag MG50048-NY
    CCL20 cDNA ORF Clone, Mouse, C-Myc tag MG50048-CM
    CCL20 cDNA ORF Clone, Mouse, N-Myc tag MG50048-NM

    CCL20 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    CCL20 cDNA ORF Clone in Cloning Vector, Human HG10485-M
    CCL20 cDNA ORF Clone, Human, untagged HG10485-UT
    CCL20 cDNA ORF Clone, Human, C-GFPSpark® tag HG10485-ACG
    CCL20 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10485-ACGLN
    CCL20 cDNA ORF Clone, Human, C-OFPSpark® tag HG10485-ACR
    CCL20 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10485-CF
    CCL20 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10485-NF
    CCL20 cDNA ORF Clone, Human, C-His tag HG10485-CH
    CCL20 cDNA ORF Clone, Human, N-His tag HG10485-NH
    CCL20 cDNA ORF Clone, Human, C-HA tag HG10485-CY
    CCL20 cDNA ORF Clone, Human, N-HA tag HG10485-NY
    CCL20 cDNA ORF Clone, Human, C-Myc tag HG10485-CM
    CCL20 cDNA ORF Clone, Human, N-Myc tag HG10485-NM
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