AKR1C2 cDNA ORF Clone, Human, C-Myc tag

Cat: HG14175-CM
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AKR1C2 cDNA ORF Clone, Human, C-Myc tag General Information
Gene
Species
Human
NCBI Ref Seq
RefSeq ORF Size
972 bp
Description
Full length Clone DNA of Human aldo-keto reductase family 1, member C2 with C terminal Myc tag.
Plasmid
Promoter
Enhanced CMV promoter
Vector
pCMV3-C-Myc
Tag Sequence
Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG
Sequencing Primers
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Kanamycin
Antibiotic in Mammalian cell
Hygromycin
Application
Stable or Transient mammalian expression
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

AKR1C2 cDNA ORF Clone, Human, C-Myc tag Alternative Names
AKR1C-pseudo cDNA ORF Clone, Human;AKR1C2 cDNA ORF Clone, Human;BABP cDNA ORF Clone, Human;DD cDNA ORF Clone, Human;DD-2 cDNA ORF Clone, Human;DD/BABP cDNA ORF Clone, Human;DD2 cDNA ORF Clone, Human;DDH2 cDNA ORF Clone, Human;HAKRD cDNA ORF Clone, Human;HBAB cDNA ORF Clone, Human;MCDR2 cDNA ORF Clone, Human;SRXY8 cDNA ORF Clone, Human;TDD cDNA ORF Clone, Human
AKR1C2 Background Information

AKR1C2 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. AKR1C2 gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for AKR1C2 gene.

Full Name
aldo-keto reductase family 1, member C2
References
  • Jin Y. et al., 2011, Biochem J. 437 (1): 53-61.
  • Veilleux A. et al., 2012, Am J Physiol Endocrinol Metab. 302 (8): E941-9.
  • Kuang P. et al., 2012, Lung Cancer. 77 (2): 427-32.
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