|A3AR, AD026, bA552M11.5, RP11-552M11.7|
|Verified forward and reverse primers for analyzing the quantitative expression of gene|
|The primer mix has been verified to generate satisfactory qPCR data on Roche LightCycler480|
|1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions) is shipped at ambiente temperatura.|
Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Adenosine A3 receptor (A3AR) is a Gi-protein-coupled receptor that, when being activated, decreases intracellular cAMP levels. The A3AR gene contains 2 exons that are separated by a single intron of approximately 2.2 kb, located on human chromosome 1p21-p13. There is extensive evidence for the involvement of A3AR in a number of pathophysiological processes including ischemic conditions of the central nervous system and heart and inflammatory states, such as rheumatoid arthritis (RA), Crohn's disease, and tumors. Therefore, A3AR is an important target for a number of inflammatory, neoplastic, and neurodegenerative conditions.