ADK cDNA ORF Clone, Human, N-Myc tag

Cat: HG13149-NM
Contact us:
+86-400-890-9989
order@sinobiological.com
Distributors
All ADK Reagents
CRO Services
Product recommended

All ADK Reagents
ADK cDNA ORF Clone, Human, N-Myc tag General Information
Gene
Species
Human
NCBI Ref Seq
RefSeq ORF Size
1038 bp
Description
Full length Clone DNA of Human adenosine kinase with N terminal Myc tag.
Plasmid
Promoter
Enhanced CMV promoter
Vector
pCMV3-N-Myc
Tag Sequence
Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG
Sequencing Primers
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Kanamycin
Antibiotic in Mammalian cell
Hygromycin
Application
Stable or Transient mammalian expression
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

ADK cDNA ORF Clone, Human, N-Myc tag Alternative Names
AK cDNA ORF Clone, Human
ADK Background Information

Adenosine kinase(ADK) belongs to the family of transferases. Adenosine kinase (ADK) is the key enzyme in adenosine metabolism and catalyzes ATP and adenosine into two products: ADP and AMP. Two isoforms of the enzyme adenosine kinase (ADK), which differ at their N-terminal ends, are found in mammalian cells. It has been shown that the two ADK isoforms differ only in their first exons and the promoter regions; hence they arise via differential splicing of their first exons with the other exons common to both isoforms. In adult brain, ADK is primarily present in astrocytes. Several lines of experimental evidence support a critical role of ADK in different types of brain injury associated with astrogliosis, which is also a prominent morphologic feature of temporal lobe epilepsy (TLE). It has been suggested that dysregulation of ADK in astrocytes is a common pathologic hallmark of TLE. Moreover, in vitro data suggest the existence of an additional layer of modulatory crosstalk between the astrocyte-based adenosine cycle and inflammation. ADK also contributes to CK homeostasis in vivo. 

Full Name
adenosine kinase
References
  • Aronica E, et al. (2011) Upregulation of adenosine kinase in astrocytes in experimental and human temporal lobe epilepsy. Epilepsia.52 (9): 1645-55.
  • Kuettel S, et al. (2011) Crystal structures of T. b. rhodesiense adenosine kinase complexed with inhibitor and activator: implications for catalysis and hyperactivation. PLoS Negl Trop Dis. 5 (5): e1164.
  • Cui XA, et al. (2011) Molecular characterization of Chinese hamster cells mutants affected in adenosine kinase and showing novel genetic and biochemical characteristics. BMC Biochem. 12 (1): 22.
  • ADK cDNA ORF Clone, Rat, Related Products

    Product Name Catalog#(PDF)
    ADK cDNA ORF Clone in Cloning Vector, Rat RG80662-U
    ADK cDNA ORF Clone, Rat, untagged RG80662-UT
    ADK Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG80662-ACGLN
    ADK cDNA ORF Clone, Rat, C-GFPSpark® tag RG80662-ACG
    ADK cDNA ORF Clone, Rat, N-GFPSpark® tag RG80662-ANG
    ADK cDNA ORF Clone, Rat, C-OFPSpark® tag RG80662-ACR
    ADK cDNA ORF Clone, Rat, N-OFPSpark® tag RG80662-ANR
    ADK cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80662-CF
    ADK cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80662-NF
    ADK cDNA ORF Clone, Rat, C-His tag RG80662-CH
    ADK cDNA ORF Clone, Rat, N-His tag RG80662-NH
    ADK cDNA ORF Clone, Rat, C-HA tag RG80662-CY
    ADK cDNA ORF Clone, Rat, N-HA tag RG80662-NY
    ADK cDNA ORF Clone, Rat, C-Myc tag RG80662-CM
    ADK cDNA ORF Clone, Rat, N-Myc tag RG80662-NM
    ADK qPCR Primer Pairs, Rat RP300626

    ADK cDNA ORF Clone, Mouse, Related Products

    Product Name Catalog#(PDF)
    ADK cDNA ORF Clone in Cloning Vector, Mouse MG51572-U
    ADK cDNA ORF Clone, Mouse, untagged MG51572-UT
    ADK Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51572-ACGLN
    ADK cDNA ORF Clone, Mouse, C-GFPSpark® tag MG51572-ACG
    ADK cDNA ORF Clone, Mouse, N-GFPSpark® tag MG51572-ANG
    ADK cDNA ORF Clone, Mouse, C-OFPSpark® tag MG51572-ACR
    ADK cDNA ORF Clone, Mouse, N-OFPSpark® tag MG51572-ANR
    ADK cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG51572-CF
    ADK cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG51572-NF
    ADK cDNA ORF Clone, Mouse, C-His tag MG51572-CH
    ADK cDNA ORF Clone, Mouse, N-His tag MG51572-NH
    ADK cDNA ORF Clone, Mouse, C-HA tag MG51572-CY
    ADK cDNA ORF Clone, Mouse, N-HA tag MG51572-NY
    ADK cDNA ORF Clone, Mouse, C-Myc tag MG51572-CM
    ADK cDNA ORF Clone, Mouse, N-Myc tag MG51572-NM
    ADK qPCR Primer Pairs, Mouse MP201455

    ADK cDNA ORF Clone, Human, Related Products

    Product Name Catalog#(PDF)
    ADK cDNA ORF Clone in Cloning Vector, Human HG13149-G
    ADK cDNA ORF Clone, Human, untagged HG13149-UT
    ADK Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG13149-ACGLN
    ADK cDNA ORF Clone, Human, C-GFPSpark® tag HG13149-ACG
    ADK cDNA ORF Clone, Human, N-GFPSpark® tag HG13149-ANG
    ADK cDNA ORF Clone, Human, C-OFPSpark® tag HG13149-ACR
    ADK cDNA ORF Clone, Human, N-OFPSpark® tag HG13149-ANR
    ADK cDNA ORF Clone, Human, C-DDK (Flag®) tag HG13149-CF
    ADK cDNA ORF Clone, Human, N-DDK (Flag®) tag HG13149-NF
    ADK cDNA ORF Clone, Human, C-His tag HG13149-CH
    ADK cDNA ORF Clone, Human, N-His tag HG13149-NH
    ADK cDNA ORF Clone, Human, C-HA tag HG13149-CY
    ADK cDNA ORF Clone, Human, N-HA tag HG13149-NY
    ADK cDNA ORF Clone, Human, C-Myc tag HG13149-CM
    ADK qPCR Primer Pairs, Human HP102534
    info info
    添加购物车成功! 添加购物车失败!