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Hexokinase 3 Protein, Antibody, ELISA Kit, cDNA Clone

Hexokinase 3 Related Areas

Hexokinase 3 Related Pathways

Hexokinase 3 Related Product

    Hexokinase 3 Summary & Protein Information

    Hexokinase 3 Background

    Gene Summary: Encodes a hexokinase (HXK1) in the plant glucose-signaling network. Functions as a glucose sensor to interrelate nutrient, light, and hormone signaling networks for controlling growth and development in response to the changing environment.
    General information above from NCBI
    Catalytic activity: ATP + D-hexose = ADP + D-hexose 6-phosphate.
    Enzyme regulation: Hexokinase is an allosteric enzyme inhibited by its product Glc-6-P.
    Subunit structure: Monomer (By similarity).
    Domain: The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus.
    Sequence similarity: Belongs to the hexokinase family.
    General information above from UniProt

    Hexokinase-3, also known as Hexokinase type III, HKIII and HK3, is a protein which belongs to the hexokinase family. Hexokinase-3 / HK3 is an enzyme which in humans is encoded by the HK2 gene. Hexokinases phosphorylate glucose to produce glucose 6-phosphate, committing glucose to the glycolytic pathway. In mammalian tissues hexokinase exists as four isoenzymes encoded by distinct genes. These proteins are homologous and are organized in two homologous domains, with the exception of hexokinase type IV which has only one. This organization is believed to be the result of a duplication and tandem fusion event involving the gene encoding for the ancestral hexokinase. The gene encodes hexokinase-3. Similar to hexokinases-1 and hexokinases-2, this allosteric enzyme is inhibited by its product glucose 6-phosphate.

    Hexokinase 3 Alternative Name

    Hexokinase 3,HK3,HKIII,HXK3, [human]
    Hexokinase 3,HK III,Hk3,MGC143940, [mouse]

    Hexokinase 3 Related Studies

  • Palma F. et al., 1996, Mol Cell Biochem. 155: 23-9.
  • Furuta H. et al.,1996, Genomics. 36 (1): 206-9.
  • Colosimo A. et al.,1996, Cytogenet Cell Genet. 74 (3): 187-8.
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