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Heart Disease Therapeutic Targets

Protein Name Alternative Names BioChemical Class / Role Products (Cat NO)
Protein Antibody Gene cDNA clones
VEGF VEGF-A, RP1-261G23.1, MGC70609, MVCD1, VPF VEGF(Vascular endothelial growth factor ), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF-A is important for the formation of blood vessels, such as during development or in pathological conditions. 11066-HNAB   HG10008-M, HG10009-M, HG10010-M, HG11066-M
MG50159-M
PPIB         HG11004-M
FGFR1/CD331 FLT2, KAL2, BFGFR, CEK, FGFBR, FLG, FLJ99988, HBGFR, N-SAM, OGD FGFR1 (Fibroblast growth factor receptor 1), also known as fms-related tyrosine kinase-2 (FLT2) and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family.Defects in FGFR1 are the cause of several deseases, such as Kallmann syndrome type 2 (KAL2), osteoglophonic dysplasia (OGD), as well as Pfeiffer syndrome (PF). 10616-H03H, 10616-H08H   HG10616-M, MG50186-M
CDK9/CDC2L4         HG10907-M
MAP3K13 LZK, MEKK13, MGC133196       HG10634-M
PLTP HDLCQ9       HG11171-M
Carboxypeptidase A1 CPA1, CPA Carboxypeptidase A1 is secreted as a pancreatic procarboxypeptidase. In contrast to procarboxypeptidase B which was always secreted by the pancreas as a monomer, procarboxypeptidase A occurs as a monomer and/or associated to one or two functionally different proteins, such as zymogen E, and is involved in zymogen inhibition. 10504-H08H   HG10504-M
Carboxypeptidase A2 CPA2 Carboxypeptidase A2 is a secreted pancreatic procarboxy-peptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was identified with a preference towards long substrates with aromatic amino acids in their C-terminal end, particularly tryptophan. 10499-H08H   HG10499-M
Carboxypeptidase A4 CPA4, CPA3       HG10789-M