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HSP60 Protein, Antibody, ELISA Kit, cDNA Clone Products
All HSP60 Products list
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HSP60 Protein
Human HSPD1 / HSP60 Protein, Recombinant 11322-H20E Mouse HSPD1 / HSP60 Protein, Recombinant 50596-M07E -
HSP60 Antibody
HSPD1 / HSP60 Antibody (Antigen Affinity Purified) 50596-RP02 -
HSP60 ELISA Kit
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HSP60 cDNA Clone
Homo sapiens HSPD1 / HSP60 cDNA Clone HG11322-M Mouse HSPD1 / HSP60 cDNA Clone / ORF Clone MG50596-M
Browse HSP60 Protein, Antibody, ELISA Kit, cDNA Clone Products by Following Categories
HSP60 Protein, Antibody, ELISA Kit, cDNA Clone
HSP60 Protein
– Human HSP60 Protein
– Mouse HSP60 Protein
– Rat HSP60 Protein
– Rhesus HSP60 Protein
– Cynomolgus HSP60 Protein
– Canine (Dog) HSP60 Protein
– Ferret HSP60 Protein
– Bovine HSP60 Protein
HSP60 Antibody
– Human HSP60 Antibody
– Mouse HSP60 Antibody
– Rat HSP60 Antibody
– Rhesus HSP60 Antibody
– Cynomolgus HSP60 Antibody
– Canine (Dog) HSP60 Antibody
– Ferret HSP60 Antibody
– Bovine HSP60 Antibody
HSP60 ELISA Kit
– Human HSP60 ELISA Kit
– Mouse HSP60 ELISA Kit
– Rat HSP60 ELISA Kit
– Rhesus HSP60 ELISA Kit
– Cynomolgus HSP60 ELISA Kit
– Canine (Dog) HSP60 ELISA Kit
– Ferret HSP60 ELISA Kit
– Bovine HSP60 ELISA Kit
HSP60 cDNA Clone
– Human HSP60 cDNA Clone
– Mouse HSP60 cDNA Clone
– Rat HSP60 cDNA Clone
– Rhesus HSP60 cDNA Clone
– Cynomolgus HSP60 cDNA Clone
– Canine (Dog) HSP60 cDNA Clone
– Ferret HSP60 cDNA Clone
– Bovine HSP60 cDNA Clone
ELISA Antibody to HSP60
– ELISA Antibody to Human HSP60
– ELISA Antibody to Mouse HSP60
– ELISA Antibody to Rat HSP60
– ELISA Antibody to Rhesus HSP60
– ELISA Antibody to Cynomolgus HSP60
– ELISA Antibody to Canine (Dog) HSP60
– ELISA Antibody to Ferret HSP60
– ELISA Antibody to Bovine HSP60
Western Blot Antibody to HSP60
– Western Blot Antibody to Human HSP60
– Western Blot Antibody to Mouse HSP60
– Western Blot Antibody to Rat HSP60
– Western Blot Antibody to Rhesus HSP60
– Western Blot Antibody to Cynomolgus HSP60
– Western Blot Antibody to Canine (Dog) HSP60
– Western Blot Antibody to Ferret HSP60
– Western Blot Antibody to Bovine HSP60
Immunohistochemistry (IHC) Antibody to HSP60
– Immunohistochemistry (IHC) Antibody to Human HSP60
– Immunohistochemistry (IHC) Antibody to Mouse HSP60
– Immunohistochemistry (IHC) Antibody to Rat HSP60
– Immunohistochemistry (IHC) Antibody to Rhesus HSP60
– Immunohistochemistry (IHC) Antibody to Cynomolgus HSP60
– Immunohistochemistry (IHC) Antibody to Canine (Dog) HSP60
– Immunohistochemistry (IHC) Antibody to Ferret HSP60
– Immunohistochemistry (IHC) Antibody to Bovine HSP60
Flow Cytometry (FACS) Antibody to HSP60
– Flow Cytometry (FACS) Antibody to Human HSP60
– Flow Cytometry (FACS) Antibody to Mouse HSP60
– Flow Cytometry (FACS) Antibody to Rat HSP60
– Flow Cytometry (FACS) Antibody to Rhesus HSP60
– Flow Cytometry (FACS) Antibody to Cynomolgus HSP60
– Flow Cytometry (FACS) Antibody to Canine (Dog) HSP60
– Flow Cytometry (FACS) Antibody to Ferret HSP60
– Flow Cytometry (FACS) Antibody to Bovine HSP60
Antibody to HSP60
Summary for HSP60
HSP60, also known as HSPD1, is a member of the chaperonin family. HSP60 may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. It may also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. HSP60 gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.Defects in HSP60 are a cause of spastic paraplegia autosomal dominant type 13 (SPG13). Spastic paraplegia is a degenerative spinal cord disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Defects in HSP60 are the cause of leukodystrophy hypomyelinating type 4 (HLD4); also called mitochondrial HSP60 chaperonopathy or MitCHAP-60 disease. HLD4 is a severe autosomal recessive hypomyelinating leukodystrophy. HSP60 is cinically characterized by infantile-onset rotary nystagmus, progressive spastic paraplegia, neurologic regression, motor impairment, profound mental retardation. Death usually occurrs within the first two decades of life.
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