HRG (Protein|Antibody|cDNA Clone|ELISA Kit)

All HRG reagents are produced in house and quality controlled, including 6 HRG Antibody, 2 HRG ELISA, 28 HRG Gene, 2 HRG Lysate, 2 HRG Protein, 1 HRG qPCR. All HRG reagents are ready to use.

Recombinant HRG proteins are expressed by HEK293 Cells with fusion tags as C-His.

HRGantibodies are validated with different applications, which are ELISA, ELISA(Cap).

HRGcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each HRG of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

HRGELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.

HRG Protein (2)

Species

HRG Protein, Human, Recombinant (His Tag)

10836-H08H

Expression host: HEK293 Cells

Human HPRG/HRG Protein 9152

HRG Protein, Rat, Recombinant (His Tag)

81643-R08H

Expression host: HEK293 Cells

Rat HPRG/HRG Protein 6386
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HRG Antibody (6)

Application Clonality
Host

Anti-HRG Antibody

10836-MM01

Application: ELISA,ELISA(Cap)

Clonality: MAb

Anti-HRG Antibody

10836-MM23

Application: ELISA

Clonality: MAb

Anti-HRG Antibody

10836-MM02

Application: ELISA

Clonality: MAb

Anti-HRG Antibody

10836-RP03

Application: ELISA

Clonality: PAb

Anti-HRG Antibody

10836-RP04

Application: ELISA

Clonality: PAb

Anti-HRG Antibody

10836-R028

Application: ELISA

Clonality: MAb

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HRG ELISA KIT & match antibody elias pair set ( 2 )

HRG ELISA Kit, Human

KIT10836

Sensitivity: 9.70 pg/mL

Human HPRG/HRG ELISA Kit Standard Curve 81

HRG Matched ELISA Antibody Pair Set,Human

SEK10836

Assay Range: 18.75 pg/ml

Human HPRG/HRG ELISA Pair Set Standard Curve 13882

HRG cDNA Clone (28)

Human
Rat

HRG qPCR Primer (1)

HRG Lysate (2)

Histidine-rich glycoprotein, also known as HRG and HPRG, is a glycoprotein located in plasma and platelets, and contains an unusually large amount of histidine and proline. In human, five distinct domains are recognized in the mature HPRG molecule. There are two N-terminal cystatin-like modules (aa 19 - 254) and one His-Pro-rich region (aa 350 - 497) that is flanked by two Pro-rich segments (aa 276 - 321 and 498 - 525). The His-Pro-rich region contains 10 tandem repeats with an HHPHG motif, and the N- and C-termini are linked by a disulfide bond. The specific functions of HRG remain unclear, but it is known that the protein binds heme, dyes and divalent metal ions. It inhibits rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. HPRG is evolutionarily, functionally and structurally related to cleaved high molecular weight kininogen (HKa), an anti-angiogenic polypeptide that stimulates apoptosis of proliferating endothelial cells through binding to cell-surface tropomyosin. The antiangiogenic activity of the multidomain plasma protein HPRG is localized to its histidine-proline-rich (H/P) domain and has recently been shown to be mediated, at least partially, through binding to cell-surface tropomyosin in fibroblast growth factor-2-activated endothelial cells.

Protein
Antibody
ELISA
Gene
qPCR
Lysate
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