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HNMT Antibody Datasheet
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|Detection limit is 0.00975 ng/well in ELISA|
HNMT Antibody Product Information
Recombinant Human HNMT protein (Catalog#13096-H09E)
|Antibody Type :||Rabbit Polyclonal Antibody ( Antibody Purification Platform )|
|Ig Type :||
|Formulation :||0.2 μm filtered solution in PBS with 5% trehalose|
Produced in rabbits immunized with purified, recombinant Human HNMT (rh HNMT; Catalog#13096-H09E; AAH20677.1; Met 1-Ala 292). Total IgG was purified by Protein A affinity chromatography.
HNMT Antibody Usage Guide
|Western blot :||This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human HNMT in WB.|
|Direct ELISA :||This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human HNMT. The detection limit for Human HNMT is approximately 0.00975 ng/well.|
|Storage :||This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
HNMT Antibody Related Products & Topics
HNMT Antibody Background
Histamine N-methyltransferase, also known as HNMT, is a cytoplasm protein which belongs to the methyltransferase superfamily and HNMT family. Histamine N-methyltransferase (HMT, HNMT) is one of two enzymes involved in the metabolism of histamine. The other being diamine oxidase. Histamine N-methyltransferase catalyzes the methylation of histamine in the presence of S-adenosylmethionine (SAM) forming N-methylhistamine. HNMT is present in most body tissues but is not present in fluid. Histamine N-methyltransferase is encoded by a single gene which has been mapped to chromosome 2. HNMT inactivates histamine by N-methylation. HNMT plays an important role in degrading histamine and in regulating the airway response to histamine.
- Yan L., et al., 2000, Pharmacogenetics 10: 261-266.
- Horton J.R., et al., 2001, Structure 9: 837-849.
- Hillier L.W., et al., 2005, Nature 434: 724-731.
HNMT related areas, pathways, and other information