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ERBB3/HER3 Mouse MAb

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    Human ErbB3/HER3 Antibody Product Information
    Immunogen:Recombinant Human HER3 / ErbB3 Protein (Catalog#10201-H08H)
    Clone ID:1F2E10E6
    Ig Type:Mouse IgG1
    Concentration:
    Formulation:0.2 μm filtered solution in PBS
    Preparation:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human HER3 / ErbB3 (rh HER3 / ErbB3; Catalog#10201-H08H; NP_001973.2; Met 1-Thr 643). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
    Other ErbB3/HER3 Antibody Products
    Reactivity: Human  
    Application: B/N  
    • Slide 1
    10201-mhA24-500
    10201-mhA24-200
    500 µg 
    200 µg 
    Add to Cart
    Reactivity: Human  
    Application: B/N  
      10201-M908-500
      10201-M908-200
      500 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10201-MM03-F-100
      10201-MM03-F-50
      100 Tests 
      50 Tests 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  
        10201-RP01-100
        10201-RP01-200
        10201-RP01-400
        100 µg 
        200 µg 
         
        Add to Cart
        Reactivity: Human  
        Application: ELISA  WB  IP  
        • Slide 1
        • Slide 1
        10201-RP02-50
        10201-RP02-100
        10201-RP02-200
        50 µg 
        100 µg 
        200 µg 
        Add to Cart
        Reactivity: Human  
        Application: ELISA  
          10201-R016-50
          10201-R016-100
          50 µg 
          100 µg 
          Add to Cart
          Reactivity: Human  
          Application: FCM  
          • Slide 1
          10201-MM03-P-50
          10201-MM03-P-100
          50 Tests 
          100 Tests 
          Add to Cart
          Reactivity: Human  
          Application: B/N  
            10201-MA24-200
            10201-MA24-500
            200 µg 
            500 µg 
            Add to Cart
            Reactivity: Human  
            Application: ELISA  
              10201-T16-200
              10201-T16-50
              10201-T16-100
              200 µg 
              50 µg 
              100 µg 
              Add to Cart
              Reactivity: Human  
              Application: FCM  
              • Slide 1
              10201-MM03-A-50
              10201-MM03-A-100
              50 Tests 
              100 Tests 
              Add to Cart
              Reactivity: Human  
              Application: FCM  IF  ICC/IF  
              • Slide 1
              • Slide 1
              10201-MM03-200
              10201-MM03-100
              10201-MM03-50
              200 µg 
              100 µg 
              50 µg 
              Add to Cart
              Reactivity: Human  
              Application: B/N  
              • Slide 1
              10201-mh908-500
              10201-mh908-200
              500 µg 
              200 µg 
              Add to Cart
              Reactivity: Mouse  
              Application: ELISA  
                51003-R138-100
                51003-R138-50
                100 µg 
                50 µg 
                Add to Cart
                Reactivity: Mouse  
                Application: ELISA  
                  51003-R028-100
                  51003-R028-50
                  100 µg 
                  50 µg 
                  Add to Cart
                  Reactivity: Mouse  
                  Application: ELISA  
                    51003-T16-50
                    51003-T16-200
                    51003-T16-100
                    50 µg 
                    200 µg 
                    100 µg 
                    Add to Cart
                    Reactivity: Mouse  
                    Application: ELISA  
                      51003-RP01-100
                      51003-RP01-400
                      51003-RP01-200
                      100 µg 
                       
                      200 µg 
                      Add to Cart
                      Reactivity: Rat  
                      Application: ELISA  
                        80111-T16-200
                        80111-T16-50
                        80111-T16-100
                        200 µg 
                        50 µg 
                        100 µg 
                        Add to Cart
                        Reactivity: Rat  
                        Application: ELISA  
                          80111-RP01-200
                          80111-RP01-400
                          80111-RP01-100
                          200 µg 
                           
                          100 µg 
                          Add to Cart
                          Reactivity: Rhesus  
                          Application: ELISA  
                            90043-T16-50
                            90043-T16-100
                            90043-T16-200
                            50 µg 
                            100 µg 
                            200 µg 
                            Add to Cart
                            Reactivity: Rhesus  
                            Application: ELISA  
                              90043-MM05-50
                              90043-MM05-100
                              90043-MM05-200
                              50 µg 
                              100 µg 
                              200 µg 
                              Add to Cart
                              Reactivity: Rhesus  
                              Application: ELISA  
                                90043-RP01-200
                                90043-RP01-100
                                90043-RP01-400
                                200 µg 
                                100 µg 
                                 
                                Add to Cart
                                ERBB3/HER3 Background

                                ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with high affinity, and initiates the related pathway which lead to cell proliferation or differentiation. ErbB3 has been shown to implicated in numerous cancers, including prostate, bladder, and breast tumors. This protein has different isoforms derived from alternative splicing variants, and among which, the secreted isoform lacking the intermembrane region modulates the activity of membrane-bound form.

                                Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

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                                Catalog: 10201-MM01-100
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                                Datasheet & Documentation

                                All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
                                Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"