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ERBB3/HER3 Rabbit PAb , Antigen Affinity Purified

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    Rhesus ERBB3 Antibody Product Information
    Immunogen:Recombinant Rhesus HER3 / ErbB3 protein (Catalog#90043-K08H)
    Clone ID:
    Ig Type:Rabbit IgG
    Concentration:
    Endotoxin:
    Formulation:0.2 μm filtered solution in PBS
    Preparation:Produced in rabbits immunized with purified, recombinant Rhesus HER3 / ErbB3 (rh HER3 / ErbB3; Catalog#90043-K08H; XP_001113953.2; Met1-Thr643). HER3 / ErbB3 specific IgG was purified by Rhesus HER3 / ErbB3 affinity chromatography.
    Other ERBB3 Antibody Products
    Reactivity: Human  
    Application: B/N  
    • Slide 1
    10201-mhA24-500
    10201-mhA24-200
    500 µg 
    200 µg 
    Add to Cart
    Reactivity: Human  
    Application: B/N  
      10201-M908-500
      10201-M908-200
      500 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10201-MM03-F-100
      10201-MM03-F-50
      100 Tests 
      50 Tests 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  
        10201-RP01-100
        10201-RP01-200
        10201-RP01-400
        100 µg 
        200 µg 
         
        Add to Cart
        Reactivity: Human  
        Application: ELISA  WB  IP  
        • Slide 1
        • Slide 1
        10201-RP02-50
        10201-RP02-100
        10201-RP02-200
        50 µg 
        100 µg 
        200 µg 
        Add to Cart
        Reactivity: Human  
        Application: ELISA  
          10201-R016-50
          10201-R016-100
          50 µg 
          100 µg 
          Add to Cart
          Reactivity: Human  
          Application: ELISA  
            10201-MM01-50
            10201-MM01-100
            10201-MM01-200
            50 µg 
            100 µg 
            200 µg 
            Add to Cart
            Reactivity: Human  
            Application: FCM  
            • Slide 1
            10201-MM03-P-50
            10201-MM03-P-100
            50 Tests 
            100 Tests 
            Add to Cart
            Reactivity: Human  
            Application: B/N  
              10201-MA24-200
              10201-MA24-500
              200 µg 
              500 µg 
              Add to Cart
              Reactivity: Human  
              Application: ELISA  
                10201-T16-200
                10201-T16-50
                10201-T16-100
                200 µg 
                50 µg 
                100 µg 
                Add to Cart
                Reactivity: Human  
                Application: FCM  
                • Slide 1
                10201-MM03-A-50
                10201-MM03-A-100
                50 Tests 
                100 Tests 
                Add to Cart
                Reactivity: Human  
                Application: FCM  IF  ICC/IF  
                • Slide 1
                • Slide 1
                10201-MM03-200
                10201-MM03-100
                10201-MM03-50
                200 µg 
                100 µg 
                50 µg 
                Add to Cart
                Reactivity: Human  
                Application: B/N  
                • Slide 1
                10201-mh908-500
                10201-mh908-200
                500 µg 
                200 µg 
                Add to Cart
                Reactivity: Mouse  
                Application: ELISA  
                  51003-R138-100
                  51003-R138-50
                  100 µg 
                  50 µg 
                  Add to Cart
                  Reactivity: Mouse  
                  Application: ELISA  
                    51003-R028-100
                    51003-R028-50
                    100 µg 
                    50 µg 
                    Add to Cart
                    Reactivity: Mouse  
                    Application: ELISA  
                      51003-T16-50
                      51003-T16-200
                      51003-T16-100
                      50 µg 
                      200 µg 
                      100 µg 
                      Add to Cart
                      Reactivity: Mouse  
                      Application: ELISA  
                        51003-RP01-100
                        51003-RP01-400
                        51003-RP01-200
                        100 µg 
                         
                        200 µg 
                        Add to Cart
                        Reactivity: Rat  
                        Application: ELISA  
                          80111-T16-200
                          80111-T16-50
                          80111-T16-100
                          200 µg 
                          50 µg 
                          100 µg 
                          Add to Cart
                          Reactivity: Rat  
                          Application: ELISA  
                            80111-RP01-200
                            80111-RP01-400
                            80111-RP01-100
                            200 µg 
                             
                            100 µg 
                            Add to Cart
                            Reactivity: Rhesus  
                            Application: ELISA  
                              90043-MM05-50
                              90043-MM05-100
                              90043-MM05-200
                              50 µg 
                              100 µg 
                              200 µg 
                              Add to Cart
                              Reactivity: Rhesus  
                              Application: ELISA  
                                90043-RP01-200
                                90043-RP01-100
                                90043-RP01-400
                                200 µg 
                                100 µg 
                                 
                                Add to Cart

                                Anti-Histone H3 rabbit monoclonal antibody at 1:200 dilution

                                Lane A: NIH3T3 Whole Cell Lysate

                                Lane B: Hela Whole Cell Lysate

                                Lysates/proteins at 30 μg per lane.

                                Secondary

                                Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.

                                Developed using the ECL technique.

                                Performed under reducing conditions.

                                Predicted band size:15 kDa

                                Observed band size:17 kDa

                                ERBB3/HER3 Background

                                ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with high affinity, and initiates the related pathway which lead to cell proliferation or differentiation. ErbB3 has been shown to implicated in numerous cancers, including prostate, bladder, and breast tumors. This protein has different isoforms derived from alternative splicing variants, and among which, the secreted isoform lacking the intermembrane region modulates the activity of membrane-bound form.

                                Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

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                                Catalog: 90043-T16-50
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                                Datasheet & Documentation

                                All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
                                Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"