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ErbB2 / HER2 Protein & Antibody

Human Epidermal Growth Factor Receptor 2

ErbB2 / HER2 Alternative Names

HER2, HER-2, ERBB2, CD340, NEU, NGL, TKR1, c-erbB-2, HER-2/neu [Homo sapiens]

HER2, HER-2, Erbb2, Erbb-2, RP23-355L10.8, Neu, c-erbB2, c-neu, mKIAA3023 [Mus musculus]

ErbB2 / HER2 Protein & Antibody

Sino Biological offers a comprehensive set of research tools (proteins, antibodies) for EGF related research. All of our antibodies were generated with recombinant full length protein as immunogen, which ensures better binding affinity and specificity to the native protein.

ErbB2 / HER2 Protein, Recombinant

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No Price / Size
ErbB2/HER2 Human ErbB2/HER2/Fc Protein, Recombinant 10004-H02H $290 / 100µg
ErbB2/HER2 Human ErbB2/HER2 Protein, Recombinant 10004-H08H $290 / 100µg
ErbB2/HER2 Human ErbB2 / HER2 / CD340 (676-1255) Protein, Recombinant, with GST Tag 10004-H20B1 $220 / 20µg
ErbB2/HER2 Mouse ErbB2/HER2 Protein, Recombinant 50714-M08H $360 / 50µg
ErbB2/HER2 Mouse ErbB2/HER2 Protein, Recombinant 50714-M02H $130 / 100µg
ErbB2/HER2 Rat ErbB2/HER2/Fc Protein, Recombinant 80079-R02H $320 / 100µg
ErbB2/HER2 Rat ErbB2/HER2 Protein, Recombinant 80079-R08H $260 / 50µg
ErbB2/HER2 Rat ErbB2/HER2 Protein, Recombinant 80079-RCCH $350 / 50µg
ErbB2/HER2 Rhesus ErbB2/HER2/Fc Protein, Recombinant 90020-K02H $260 / 50µg
ErbB2/HER2 Rhesus ErbB2/HER2 Protein, Recombinant 90020-K08H $350 / 50µg

ErbB2 / HER2 Antibody

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No Price / Size
Human
ErbB2/HER2
ELISA Mouse Monoclonal Antibody 10004-MM01 $230 / 100µg
Human
ErbB2/HER2
ELISA Mouse Monoclonal Antibody (Biotin conjugated) 10004-MM01B $200 / 100µg
Human
ErbB2/HER2
WB Mouse Monoclonal Antibody (Biotin conjugated) 10004-MM02B $200 / 100µg
Human
ErbB2/HER2
WB, ELISA, Flow Cytometry ErbB2/HER2 Antibody, Rabbit MAb 10004-R002 $290 / 100µg
Human
ErbB2/HER2
WB, ELISA, IHC, Flow Cytometry ErbB2/HER2 Antibody, Rabbit MAb 10004-R511 $290 / 100µg
Human
ErbB2/HER2
Flow Cytometry ErbB2/HER2 Antibody, Rabbit MAb 10004-R511F $200 / 100 Tests
Human
ErbB2/HER2
WB, ELISA Rabbit Polyclonal Antibody 10004-RP03 $230 / 200µg
Human
ErbB2/HER2
WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified) 10004-RP04 $290 / 100µg
Human
ErbB2/HER2
FCM ErbB2 / HER2 / CD340 Antibody ( FITC ) 10004-MM03-F $200 / 100 Tests
Rhesus
ErbB2/HER2
WB, ELISA HER2 / ErbB2 Antibody (Antigen Affinity Purified) 90020-RP02 $290 / 100µg
Rhesus
ErbB2/HER2
WB, ELISA HER2 / ErbB2 Antibody 90020-MM01 $230 / 100µg

ErbB2 / HER2 ELISA Kit

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No Price / Size
Human ErbB2/HER2 ELISA ErbB2/HER2 ELISA Kit SEK10004 $350 / 5 Plates

ErbB2 / HER2 cDNA Clone

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No Price / Size
ErbB2/HER2 Human Homo sapiens ErbB2/HER2 transcript variant 1 cDNA Clone(NM_004448.2) HG10004-M $195
ErbB2/HER2 Mouse Mouse ErbB2/HER2 cDNA Clone / ORF Clone MG50714-G $395
HER2/ErbB2 Canine Canine ERBB2 Gene cDNA Clone / ORF Clone DG70024-G $395
ErbB2/HER2 Rat Rat HER2/ErbB2 cDNA Clone / ORF Clone RG80079-M $395
ErbB2/HER2 Rhesus Rhesus monkey HER2/ErbB2 cDNA Clone / ORF Clone CG90020-M $195

ErbB2 / HER2 Related Areas

Enzyme>>Protein Kinase>>Receptor Tyrosine Kinase>>ErbB2/HER2

Signal Transduction>>Protein Kinase>>Receptor Tyrosine Kinase>>ErbB2/HER2

Cancer>>Cancer Biomarkers>>ErbB2/HER2

Cancer>>Growth Factor & Receptor>>EGF Family & Receptor>>ErbB2/HER2

Cancer>>Growth Factor & Receptor>>Receptor Tyrosine Kinase>>ErbB2/HER2

Immunology>>Cluster of Differentiation>>Other>>ErbB2/HER2/CD340

ErbB2 / HER2 Related Products

EGF Receptor Family Protein
Molecule Species Description //For Detailed Info. and Price------CLICK! Price / Size
HER1 Human HER1 Protein, Recombinant (Met 1 - Ser 645) $130 / 20µg
HER1 Human HER1/Fc Protein, Recombinant (Met 1 - Ser 645) $290 / 100µg
HER1 Human HER1 Protein, Recombinant (Met 1 - Lys 642) $300 / 20µg
HER3 Human HER3/Fc Protein, Recombinant $290 / 100µg
HER3 Human HER3 Protein, Recombinant $350 / 20µg
HER4 Human DAN/NBL1/Fc Protein, Recombinant $290 / 100µg
EGF Ligands Protein
Molecule Species Description //For Detailed Info. and Price------CLICK! Price / Size

EGF

Human EGF/Fc Protein, Recombinant $350 / 200µg
EGF Human EGF Protein, Recombinant $120 / 500µg
EGF Receptor Family Antibody
Molecule Application Description //For Detailed Info. and Price------CLICK! Price / Size
Human
HER3/ErbB3
WB, ELISA HER3/ErbB3 Antibody, Rabbit PAb $230 / 200µg
Human
HER3/ErbB3
WB, ELISA HER3/ErbB3 Antibody, Rabbit PAb (Antigen Affinity Purified) $290 / 100µg
EGF Receptor Family cDNA Clone
Molecule Species Description //For Detailed Info. and Price------CLICK! Price / Size
HER2 Human Homo sapiens HER2 transcript variant 1 cDNA Clone(NM_004448.2) $195
HER3 Human Homo sapiens HER3 transcript variant 1 cDNA Clone(NM_001982.2) $95
HER4 Human Homo sapiens HER4 transcript variant JM-a/CVT-2 cDNA Clone(NM_001042599.1) $95
EGF Ligands cDNA Clone
Molecule Species Description //For Detailed Info. and Price------CLICK! Price / Size

EGF-L6

Hunan Homo sapiens EGF-L6 cDNA Clone(NM_015507.2) $95
EGFR/ErbB/HER1 Human Homo sapiens EGFR cDNA Clone $395

Neurexophilin-1

Human Homo sapiens Neurexophilin-1 cDNA Clone(NM_152745.2) $95

 

ErbB2 / HER2 Background

Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.

ErbB2 / HER2 Related Studies

  1. Hayes DF, et al. (2007) HER2 and response to paclitaxel in node-positive breast cancer. N Engl J Med. 357(15): 1496-506.
  2. Krawczyk N, et al. (2009) HER2 status on persistent disseminated tumor cells after adjuvant therapy may differ from initial HER2 status on primary tumor. Anticancer Res. 29(10): 4019-24.

 

ErbB2 related areas, pathways, and other information

Related Information

EGFR (ErbB1, HER1)

ErbB2 (HER2)

ErbB3 (HER3)

ErbB4 (HER4)

 

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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